This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4tli

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:46, 28 December 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
 +
==THERMOLYSIN (25% ISOPROPANOL SOAKED CRYSTALS)==
==THERMOLYSIN (25% ISOPROPANOL SOAKED CRYSTALS)==
-
<StructureSection load='4tli' size='340' side='right' caption='[[4tli]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+
<StructureSection load='4tli' size='340' side='right'caption='[[4tli]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4tli]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TLI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4tli]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TLI FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tlx|1tlx]], [[2tlx|2tlx]], [[1tli|1tli]], [[2tli|2tli]], [[3tli|3tli]], [[5tli|5tli]], [[6tli|6tli]], [[7tli|7tli]], [[8tli|8tli]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tli OCA], [https://pdbe.org/4tli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tli RCSB], [https://www.ebi.ac.uk/pdbsum/4tli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tli ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tli OCA], [http://pdbe.org/4tli PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tli RCSB], [http://www.ebi.ac.uk/pdbsum/4tli PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
+
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tl/4tli_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tl/4tli_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 31: Line 31:
==See Also==
==See Also==
-
*[[Thermolysin|Thermolysin]]
+
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 37: Line 37:
</StructureSection>
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
-
[[Category: Thermolysin]]
+
[[Category: Large Structures]]
-
[[Category: Done, S H]]
+
[[Category: Done SH]]
-
[[Category: English, A C]]
+
[[Category: English AC]]
-
[[Category: Groom, C R]]
+
[[Category: Groom CR]]
-
[[Category: Hubbard, R E]]
+
[[Category: Hubbard RE]]
-
[[Category: Hydrolase]]
+
-
[[Category: Metalloproteinase]]
+
-
[[Category: Organic solvent]]
+

Current revision

THERMOLYSIN (25% ISOPROPANOL SOAKED CRYSTALS)

PDB ID 4tli

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4tli"
Personal tools