8a3h

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[[Image:8a3h.gif|left|200px]]<br /><applet load="8a3h" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="8a3h, resolution 0.97&Aring;" />
 
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'''Cellobiose-derived imidazole complex of the endoglucanase cel5A from Bacillus agaradhaerens at 0.97 A resolution'''<br />
 
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==About this Structure==
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==Cellobiose-derived imidazole complex of the endoglucanase cel5A from Bacillus agaradhaerens at 0.97 A resolution==
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8A3H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=IDC:'>IDC</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A3H OCA].
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<StructureSection load='8a3h' size='340' side='right'caption='[[8a3h]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
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[[Category: Bacillus agaradhaerens]]
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== Structural highlights ==
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[[Category: Cellulase]]
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<table><tr><td colspan='2'>[[8a3h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salipaludibacillus_agaradhaerens Salipaludibacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A3H FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.97&#8491;</td></tr>
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[[Category: Davies, G J.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IDC:5-HYDROXYMETHYL-5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-6YL-7,8-DIOL-GLUCOPYRANOSIDE'>IDC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Pipelier, M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a3h OCA], [https://pdbe.org/8a3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a3h RCSB], [https://www.ebi.ac.uk/pdbsum/8a3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a3h ProSAT]</span></td></tr>
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[[Category: Schulein, M.]]
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</table>
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[[Category: Varrot, A.]]
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== Function ==
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[[Category: Vasella, A.]]
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[https://www.uniprot.org/uniprot/GUN5_SALAG GUN5_SALAG]
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[[Category: ACT]]
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== Evolutionary Conservation ==
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[[Category: GOL]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: IDC]]
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Check<jmol>
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[[Category: SO4]]
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<jmolCheckbox>
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[[Category: cellulose degradation]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/8a3h_consurf.spt"</scriptWhenChecked>
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[[Category: endoglucanase]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: glycoside hydrolase family 5]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: lateral protonation]]
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</jmolCheckbox>
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[[Category: transition state analogue]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=8a3h ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:17:40 2008''
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==See Also==
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Salipaludibacillus agaradhaerens]]
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[[Category: Davies GJ]]
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[[Category: Pipelier M]]
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[[Category: Schulein M]]
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[[Category: Varrot A]]
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[[Category: Vasella A]]

Current revision

Cellobiose-derived imidazole complex of the endoglucanase cel5A from Bacillus agaradhaerens at 0.97 A resolution

PDB ID 8a3h

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