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2v6q
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2v6q' size='340' side='right' caption='[[2v6q]], [[Resolution|resolution]] 2.70Å' scene=''> | + | ==Crystal Structure of a BHRF-1 : Bim BH3 complex== |
| + | <StructureSection load='2v6q' size='340' side='right'caption='[[2v6q]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2v6q]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2v6q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V6Q FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v6q OCA], [https://pdbe.org/2v6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v6q RCSB], [https://www.ebi.ac.uk/pdbsum/2v6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v6q ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EAR_EBVG EAR_EBVG] Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2v6q" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Human | + | [[Category: Human gammaherpesvirus 4]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Colman PM]] |
| - | [[Category: | + | [[Category: Huang DCS]] |
| - | [[Category: | + | [[Category: Kvansakul M]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of a BHRF-1 : Bim BH3 complex
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