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Transcriptional activator 3D structures

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Current revision (08:13, 1 January 2024) (edit) (undo)
 
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Line 14: Line 14:
**[[1mse]], [[1msf]] – mTA DBD 90-193 + DNA – NMR - mouse<br />
**[[1mse]], [[1msf]] – mTA DBD 90-193 + DNA – NMR - mouse<br />
-
**1mbe]], [[1mbf]] – mTA DBD repeat 1 + DNA - NMR<br />
+
**[[1mbe]], [[1mbf]] – mTA DBD repeat 1 + DNA - NMR<br />
-
**[1mbg]], [[1mbh]] – mTA DBD repeat 2 + DNA - NMR<br />
+
**[[1mbg]], [[1mbh]] – mTA DBD repeat 2 + DNA - NMR<br />
**[[1mbj]], [[1mbk]] – mTA DBD repeat 3 + DNA - NMR<br />
**[[1mbj]], [[1mbk]] – mTA DBD repeat 3 + DNA - NMR<br />
**[[1h88]] – mTA DBD + DNA + CCAAT/enhancer binding protein β<br />
**[[1h88]] – mTA DBD + DNA + CCAAT/enhancer binding protein β<br />
Line 29: Line 29:
*Psp operon TA
*Psp operon TA
-
**[[2bjw]] – EcTA AAA domain – Escherichia coli<br />
+
**[[2bjw]] – EcTA AAA domain –'' Escherichia coli''<br />
-
 
+
**[[4qnr]] – EcTA AAA domain (mutant) + ATP<br />
**[[4qnr]] – EcTA AAA domain (mutant) + ATP<br />
**[[4qos]] – EcTA AAA domain (mutant) + ADP<br />
**[[4qos]] – EcTA AAA domain (mutant) + ADP<br />
Line 40: Line 39:
*TenA TA
*TenA TA
-
**[[1tyh]], [[1yaf]] – BsTA – Bacillus subtilis<br />
+
**[[1tyh]], [[1yaf]] – BsTA – ''Bacillus subtilis''<br />
-
**[[2qzc]] – TA – Sulfolobus solfataricus<br />
+
**[[2qzc]] – TA – ''Sulfolobus solfataricus''<br />
-
**[[3no6]] – TA – Staphylococcus epidermidis<br />
+
**[[3no6]] – TA – ''Staphylococcus epidermidis''<br />
**[[1yak]] – BsTA + pyrimidine derivative<br />
**[[1yak]] – BsTA + pyrimidine derivative<br />
**[[2qcx]] – BsTA (mutant) + pyrimidine derivative<br />
**[[2qcx]] – BsTA (mutant) + pyrimidine derivative<br />
-
**[[1udd]] – TA – Pyrococcus horikishii<br />
+
**[[1udd]] – TA – ''Pyrococcus horikishii''<br />
*LasR TA or transcriptional regulator LasR
*LasR TA or transcriptional regulator LasR
-
**[[6mww]] – PaTA – Pseudomonas aeruginosa<br />
+
**[[6mww]] – PaTA – ''Pseudomonas aeruginosa''<br />
**[[2uv0]] – PaTA LBD residues 1-173 <br />
**[[2uv0]] – PaTA LBD residues 1-173 <br />
**[[3ix3]], [[6mvn]], [[6mvm]] – PaTA LBD + oxo-dodecanoyl-homoserine lactone<br />
**[[3ix3]], [[6mvn]], [[6mvm]] – PaTA LBD + oxo-dodecanoyl-homoserine lactone<br />
Line 70: Line 69:
**[[2yje]], [[2yjf]] – mTA Rpel domain + actin <br />
**[[2yje]], [[2yjf]] – mTA Rpel domain + actin <br />
-
Brg1 TA
+
*Brg1 TA
**[[5ea1]] – hTA bromodomain 1418-1536 - human<br />
**[[5ea1]] – hTA bromodomain 1418-1536 - human<br />
Line 78: Line 77:
**[[2i8b]] – TA C terminal – Zaire ebolavirus<br />
**[[2i8b]] – TA C terminal – Zaire ebolavirus<br />
**[[3v7o]] – TA C terminal – Reston ebolavirus<br />
**[[3v7o]] – TA C terminal – Reston ebolavirus<br />
- 
*Flagelar TA
*Flagelar TA
Line 88: Line 86:
*Tipa TA
*Tipa TA
-
**[[1ny9]] – SlTA antibiotic binding domain – Streptomyces lividans - NMR<br />
+
**[[1ny9]] – SlTA antibiotic binding domain – ''Streptomyces lividans'' - NMR<br />
**[[2mbz]], [[2mc0]] - SlTA antibiotic binding domain + thiopeptide - NMR<br />
**[[2mbz]], [[2mc0]] - SlTA antibiotic binding domain + thiopeptide - NMR<br />
- 
- 
**[[1r8d]] – BsTA <br />
**[[1r8d]] – BsTA <br />
Line 104: Line 100:
**[[2zhh]] – EcTA <br />
**[[2zhh]] – EcTA <br />
**[[2zhg]] – EcTA + DNA<br />
**[[2zhg]] – EcTA + DNA<br />
-
**[[6tf4]] – VcTA C terminal - Vibrio cholera - NMR<br />
+
**[[6tf4]] – VcTA C terminal - ''Vibrio cholera'' - NMR<br />
*GlxR TA
*GlxR TA
-
**[[3r6s]] – CgTA +cAMP – Corynebacterium glutamicum <br />
+
**[[3r6s]] – CgTA +cAMP – ''Corynebacterium glutamicum'' <br />
**[[4byy]] – CgTA <br />
**[[4byy]] – CgTA <br />
*OxyR TA or hydrogen peroxide-inducible genes activator
*OxyR TA or hydrogen peroxide-inducible genes activator
-
**[[3t22]], [[3ho7]], [[3uki]] – TA regulatory domain – Porphyromonas gingivalis <br />
+
**[[3t22]], [[3ho7]], [[3uki]] – TA regulatory domain – ''Porphyromonas gingivalis'' <br />
-
**[[7l4s]] – TA regulatory domain – Shewnella oneidensis<br />
+
**[[7l4s]] – TA regulatory domain – ''Shewnella oneidensis''<br />
**[[4y0m]] – PaTA regulatory domain <br />
**[[4y0m]] – PaTA regulatory domain <br />
**[[4x6g]], [[4xws]] – PaTA regulatory domain (mutant)<br />
**[[4x6g]], [[4xws]] – PaTA regulatory domain (mutant)<br />
Line 120: Line 116:
**[[6g1d]] – CgTA regulatory domain (mutant)<br />
**[[6g1d]] – CgTA regulatory domain (mutant)<br />
**[[6g1b]], [[6g4r]] – CgTA regulatory domain + H2O2<br />
**[[6g1b]], [[6g4r]] – CgTA regulatory domain + H2O2<br />
-
**[[5x0v]] – VvTA - Vibrio vulnificus<br />
+
**[[5x0v]] – VvTA - ''Vibrio vulnificus''<br />
**[[5b70]], [[5b7d]], [[5b7h]], [[5x0q]] – VvTA (mutant) <br />
**[[5b70]], [[5b7d]], [[5b7h]], [[5x0q]] – VvTA (mutant) <br />
-
**[[3jv9]] – NmTA – Neisseria meningitidis <br />
+
**[[3jv9]] – NmTA – ''Neisseria meningitidis'' <br />
*PlcR TA
*PlcR TA
-
**[[4fsc]] – BtTA - Bacillus thuringiensis <br />
+
**[[4fsc]] – BtTA - ''Bacillus thuringiensis'' <br />
**[[2qfc]] – BtTA + PapR peptide <br />
**[[2qfc]] – BtTA + PapR peptide <br />
**[[3u3w]] – BtTA + DNA + PapR peptide <br />
**[[3u3w]] – BtTA + DNA + PapR peptide <br />
Line 132: Line 128:
*VirB TA or virulence regulon transcriptional activator VirB
*VirB TA or virulence regulon transcriptional activator VirB
-
**[[3vwb]], [[3w2a]], [[3w3c]] – TA core domain + DNA – Shigella flexneri<br />
+
**[[3vwb]], [[3w2a]], [[3w3c]] – TA core domain + DNA – ''Shigella flexneri''<br />
*MafA TA
*MafA TA
Line 140: Line 136:
*CysB TA or Cys regulon transcriptional activator CysB
*CysB TA or Cys regulon transcriptional activator CysB
-
**[[4gwo]], [[4gxa]], [[4lon]], [[4lp2]] – StTA C terminal – Salmonella typhimurium<br />
+
**[[4gwo]], [[4gxa]], [[4lon]], [[4lp2]] – StTA C terminal – ''Salmonella typhimurium''<br />
**[[4lq2]], [[4lq5]], [[4m4g]] – StTA C terminal + acetylserine<br />
**[[4lq2]], [[4lq5]], [[4m4g]] – StTA C terminal + acetylserine<br />
-
**[[1al3]] – TA cofactor binding domain – Klebsiella aerogenes<br />
+
**[[1al3]] – TA cofactor binding domain – ''Klebsiella aerogenes''<br />
**[[5z50]] – PaTA regulatory domain <br />
**[[5z50]] – PaTA regulatory domain <br />
**[[5z4y]], [[5z4z]] – PaTA NTD domain <br />
**[[5z4y]], [[5z4z]] – PaTA NTD domain <br />
Line 156: Line 152:
**[[6uue]], [[6utc]] – VvTA <br />
**[[6uue]], [[6utc]] – VvTA <br />
**[[7nmb]], [[7nn6]] – VcTA - NMR<br />
**[[7nmb]], [[7nn6]] – VcTA - NMR<br />
 +
**[[8b4b]], [[8b4c]], [[8b4d]], [[8b4e]] – VcTA + DNA<br />
 +
**[[8alo]] – VcTA + ToxS<br />
*LysR TA
*LysR TA
Line 165: Line 163:
**[[6yiz]], [[7nbw]] – PaTA + agonist<br />
**[[6yiz]], [[7nbw]] – PaTA + agonist<br />
**[[5z7h]] – SaTA <br />
**[[5z7h]] – SaTA <br />
-
**[[4pzj]] – TA – Eggerthella lenta<br />
+
**[[4pzj]] – TA – ''Eggerthella lenta''<br />
**[[3hhf]], [[3hhg]], [[4ab5]] – NmTA <br />
**[[3hhf]], [[3hhg]], [[4ab5]] – NmTA <br />
-
**[[3fzj]] – TA – Comamonas testosteroni<br />
+
**[[3fzj]] – TA – ''Comamonas testosteroni''<br />
-
**[[1ixc]], [[1iz1]] – CnTA – Cupriavidus necator<br />
+
**[[1ixc]], [[1iz1]] – CnTA – ''Cupriavidus necator''<br />
**[[5xxp]], [[7d98]] – CnTA + DNA<br />
**[[5xxp]], [[7d98]] – CnTA + DNA<br />
-
**[[1uth]], [[2y7r]], [[5ae4]] – TA – Burkholderia cepacia<br />
+
**[[1uth]], [[2y7r]], [[5ae4]] – TA – ''Burkholderia cepacia''<br />
-
**[[7trv]], [[7trw]] – TA LBD – Yersinia pestis<br />
+
**[[7trv]], [[7trw]] – TA LBD – ''Yersinia pestis''<br />
-
**[[7erp]], [[7erq]] – CsTA regulatory domain – Cronobacter sakazakii<br />
+
**[[7erp]], [[7erq]] – CsTA regulatory domain – ''Cronobacter sakazakii''<br />
**[[7fdf]] – CsTA regulatory domain (mutant) <br />
**[[7fdf]] – CsTA regulatory domain (mutant) <br />
Line 178: Line 176:
**[[4lmg]] – yTA + DNA<br />
**[[4lmg]] – yTA + DNA<br />
- 
*Mga TA
*Mga TA
-
**[[5way]] – SpTA – Streptococcus pneumoniae<br />
+
**[[5way]] – SpTA – ''Streptococcus pneumoniae''<br />
-
 
+
*Spt7 TA
*Spt7 TA
Line 191: Line 187:
*Quorum-sensing TA or TraR
*Quorum-sensing TA or TraR
-
**[[5l07]] – YeTA – Yersinia enterocolitica<br />
+
**[[5l07]] – YeTA – ''Yersinia enterocolitica''<br />
**[[5l09]] – YeTA + THF derivative<br />
**[[5l09]] – YeTA + THF derivative<br />
-
**[[1l3l]] – AtTA + pheromone + DNA – Agrobacterium tumefaciens <br />
+
**[[1l3l]] – AtTA + pheromone + DNA – ''Agrobacterium tumefaciens'' <br />
**[[1h0m]] – AtTA + auto-inducer + DNA <br />
**[[1h0m]] – AtTA + auto-inducer + DNA <br />
Line 202: Line 198:
*ComR TA
*ComR TA
-
**[[5juf]], [[6qer]] – StTA – Streptococcus thermophilus<br />
+
**[[5juf]], [[6qer]] – StTA – ''Streptococcus thermophilus''<br />
**[[5jub]] – StTA + DNA<br />
**[[5jub]] – StTA + DNA<br />
-
**[[5fd4]] – TA – Streptococcus suis<br />
+
**[[5fd4]] – TA – ''Streptococcus suis''<br />
-
**[[7n10]], [[7n1n]] – SmTA DBD + Prx – Streptococcus mutans<br />
+
**[[7n10]], [[7n1n]] – SmTA DBD + Prx – ''Streptococcus mutans''<br />
-
**[[6hu8]] – SvTA – Streptococcus vestibularis<br />
+
**[[6hu8]] – SvTA – ''Streptococcus vestibularis''<br />
**[[6hua]] – SvTA + peptide<br />
**[[6hua]] – SvTA + peptide<br />
*FasR TA
*FasR TA
-
**[[6o6p]] – MtTA + DNA – Mycobacterium tuberculosis<br />
+
**[[6o6p]] – MtTA + DNA – ''Mycobacterium tuberculosis''<br />
**[[6o6o]] – MtTA + myristic acid<br />
**[[6o6o]] – MtTA + myristic acid<br />
**[[6o6n]] – MtTA + arachinoyl-CoA<br />
**[[6o6n]] – MtTA + arachinoyl-CoA<br />
- 
*ModE TA
*ModE TA
Line 223: Line 218:
*TetR family TA
*TetR family TA
-
**[[1z77]], [[2id6]], [[2iek]], [[1zkg]], [[4i76]], [[3ih2]], [[3ih3]], [[3ih4]] – TmTA – Thermotoga maritima<br />
+
**[[1z77]], [[2id6]], [[2iek]], [[1zkg]], [[4i76]], [[3ih2]], [[3ih3]], [[3ih4]] – TmTA – ''Thermotoga maritima''<br />
**[[4i6z]] – TmTA + DNA<br />
**[[4i6z]] – TmTA + DNA<br />
-
**[[1zk8]], [[2fq4]], [[4me9]] – BcTA – Bacillus cereus<br />
+
**[[1zk8]], [[2fq4]], [[4me9]] – BcTA – ''Bacillus cereus''<br />
-
**[[3cwr]] – TA – Rhodspirillum rubrum<br />
+
**[[3cwr]] – TA – ''Rhodspirillum rubrum''<br />
-
**[[1z0x]] – EfTA – Enterococcus faecalis<br />
+
**[[1z0x]] – EfTA – ''Enterococcus faecalis''<br />
-
**[[3c2b]] – AfTA – Agrobacterium fabrum<br />
+
**[[3c2b]] – AfTA – ''Agrobacterium fabrum''<br />
**[[2o7t]] – CgTA <br />
**[[2o7t]] – CgTA <br />
**[[2g7s]] – AtTA <br />
**[[2g7s]] – AtTA <br />
-
**[[3gzi]] – TA – Shewanella loihica<br />
+
**[[3gzi]] – TA – ''Shewanella loihica''<br />
-
**[[2qib]], [[2zcx]], [[6srm]] – ScTA – Streptomyces coelicolor<br />
+
**[[2qib]], [[2zcx]], [[7ky1]] – ScTA – ''Streptomyces coelicolor''<br />
-
**[[2hyt]] – TA – Pectobacterium atrosepticum<br />
+
**[[2hyt]] – TA – ''Pectobacterium atrosepticum''<br />
-
**[[3cdl]] – PsTA – Pseudomonas syringae<br />
+
**[[3cdl]] – PsTA – ''Pseudomonas syringae''<br />
-
**[[3kkc]] – SaTA – Streptococcus agalactiae<br />
+
**[[3kkc]] – SaTA – ''Streptococcus agalactiae''<br />
-
**[[3nnr]] – TA – Marinobacter aquaeolei<br />
+
**[[3nnr]] – TA – ''Marinobacter aquaeolei''<br />
-
**[[3on4]] – TA – Legionella pneumophila<br />
+
**[[3on4]] – TA – ''Legionella pneumophila''<br />
-
**[[3f1b]] – RjTA – Rhodococcus jostii<br />
+
**[[3f1b]] – RjTA – ''Rhodococcus jostii''<br />
-
**[[3eup]] – TA – Cytophaga hutchinsonii<br />
+
**[[3eup]] – TA – ''Cytophaga hutchinsoni''i<br />
-
**[[3egq]] – TA – Archaeoglobus fulgidus<br />
+
**[[3egq]] – TA – ''Archaeoglobus fulgidus''<br />
**[[4hku]] – LmTA – Listeria monocytogenes<br />
**[[4hku]] – LmTA – Listeria monocytogenes<br />
-
**[[3nrg]], [[3qbm]] – TA – Chlotoflexus aurantiacus<br />
+
**[[3nrg]], [[3qbm]] – TA – ''Chlotoflexus aurantiacus''<br />
**[[6nsr]] – PaTA (mutant) + DNA<br />
**[[6nsr]] – PaTA (mutant) + DNA<br />
-
**[[4jkz]] – MsTA – Mycobacterium smegmatis<br />
+
**[[4jkz]] – MsTA – ''Mycobacterium smegmatis''<br />
-
**[[6el2]] – SacTA – Sulfolobus acidocaldarius<br />
+
**[[6el2]] – SacTA – ''Sulfolobus acidocaldarius''<br />
**[[6en8]] – SacTA + DNA<br />
**[[6en8]] – SacTA + DNA<br />
Line 252: Line 247:
**[[2rae]] – RjTA <br />
**[[2rae]] – RjTA <br />
**[[3lhq]] – StTA <br />
**[[3lhq]] – StTA <br />
-
**[[3b81]] – CpTA – Clostridium acetobutylicum<br />
+
**[[3b81]] – CpTA – ''Clostridium acetobutylicum''<br />
-
**[[3dcf]] – TA – Thermobifida fusca<br />
+
**[[3dcf]] – TA – ''Thermobifida fusca''<br />
**[[3mvp]] – SmTA <br />
**[[3mvp]] – SmTA <br />
**[[5d18]], [[5d19]], [[6a4l]], [[6a4w]] – MtTA <br />
**[[5d18]], [[5d19]], [[6a4l]], [[6a4w]] – MtTA <br />
-
**[[2eh3]] – TA – Aquifex aeolicus<br />
+
**[[2eh3]] – TA – ''Aquifex aeolicus''<br />
-
**[[3vuq]] – TtTA – Thermus thermophilus<br />
+
**[[3vuq]] – TtTA – ''Thermus thermophilus''<br />
-
**[[7eqe]] – SgTA – Streptococcus griseus<br />
+
**[[7eqe]] – SgTA – ''Streptococcus griseus''<br />
**[[7eqf]] – SgTA + ligand<br />
**[[7eqf]] – SgTA + ligand<br />
-
**[[5gp9]], [[5gpa]] – BhTA – Bacillus halodurans<br />
+
**[[5gp9]], [[5gpa]] – BhTA – ''Bacillus halodurans''<br />
**[[5gpc]] – BhTA + DNA <br />
**[[5gpc]] – BhTA + DNA <br />
-
**[[6g87]] – BdTA – Bradyrhizobium diazoefficiens<br />
+
**[[6g87]] – BdTA – ''Bradyrhizobium diazoefficiens''<br />
**[[6g8h]] – BdTA + naringenin <br />
**[[6g8h]] – BdTA + naringenin <br />
**[[6g8g]] – BdTA + genistein <br />
**[[6g8g]] – BdTA + genistein <br />
Line 273: Line 268:
**[[3c7j]] – PsTA <br />
**[[3c7j]] – PsTA <br />
**[[2di3]], [[2p19]] – CgTA <br />
**[[2di3]], [[2p19]] – CgTA <br />
-
**[[3tqn]] – TA – Coxiella burnetii<br />
+
**[[3tqn]] – TA –'' Coxiella burnetii''<br />
**[[6za0]], [[6za3]], [[7za7]] – AfTA <br />
**[[6za0]], [[6za3]], [[7za7]] – AfTA <br />
**[[6z74]], [[6zab]] – AfTA + DNA<br />
**[[6z74]], [[6zab]] – AfTA + DNA<br />
-
**[[7u5q]] – TA – Brucella melitensis<br />
+
**[[7u5q]] – TA – ''Brucella melitensis''<br />
**[[6sbs]] – SacTA <br />
**[[6sbs]] – SacTA <br />
-
**[[3h5o]] – TA – Chromobacterium violaceum <br />
+
**[[3h5o]] – TA – ''Chromobacterium violaceum'' <br />
**[[6az6]], [[7b5t]], [[7b5y]], [[7b5w]] – SaTA <br />
**[[6az6]], [[7b5t]], [[7b5y]], [[7b5w]] – SaTA <br />
**[[7b5u]] – SaTA + diAMP <br />
**[[7b5u]] – SaTA + diAMP <br />
**[[7oz3]] – SaTA + DNA – Cryo EM<br />
**[[7oz3]] – SaTA + DNA – Cryo EM<br />
**[[4r1h]] – LmTA <br />
**[[4r1h]] – LmTA <br />
-
**[[3ihu]] – TA – Ralstonia eutropha <br />
+
**[[3ihu]] – TA – ''Ralstonia eutropha'' <br />
-
**[[3lhe]] – TA – Bacillus anthracis <br />
+
**[[3lhe]] – TA – ''Bacillus anthracis'' <br />
**[[3f8m]] – MsTA <br />
**[[3f8m]] – MsTA <br />
*MarR family TA or multiple antibiotic resistance protein
*MarR family TA or multiple antibiotic resistance protein
-
**[[3boq]], [[3cjn]], [[3e6m]] – RpTA - Ruegeria pomeryi<br />
+
**[[3boq]], [[3cjn]], [[3e6m]] – RpTA - ''Ruegeria pomeryi''<br />
-
**[[3s2w]] – TA – Methanosarcina mazei <br />
+
**[[3s2w]] – TA – ''Methanosarcina mazei'' <br />
-
**[[3bpv]] – TA – Methanobacterium thermoautotrophicum <br />
+
**[[3bpv]] – TA – ''Methanobacterium thermoautotrophicum'' <br />
-
**[[2fbk]] – DrTA – Deinococcus radiodurans<br />
+
**[[2fbk]] – DrTA –'' Deinococcus radiodurans''<br />
**[[5dd8]] – DrTA (mutant) <br />
**[[5dd8]] – DrTA (mutant) <br />
-
**[[2fa5]] – TA – Xanthomonas campestris<br />
+
**[[2fa5]] – TA – ''Xanthomonas campestris''<br />
**[[3g3z]], [[5aiq]] – NmTA <br />
**[[3g3z]], [[5aiq]] – NmTA <br />
**[[5aip]] – NmTA + hydroxyphenylacetate <br />
**[[5aip]] – NmTA + hydroxyphenylacetate <br />
-
**[[5e1w]] – DmTA – Dihalococcoides mccartyi<br />
+
**[[5e1w]] – DmTA – ''Dihalococcoides mccartyi''<br />
**[[5e1z]], [[5e1x]], [[5e20]] – DmTA + phenol derivative <br />
**[[5e1z]], [[5e1x]], [[5e20]] – DmTA + phenol derivative <br />
-
**[[6c28]] – RpTA + coumaroyl-CoA – Rhodopseudomonas palustris <br />
+
**[[6c28]] – RpTA + coumaroyl-CoA – ''Rhodopseudomonas palustris'' <br />
**[[3fm5]] – RjTA <br />
**[[3fm5]] – RjTA <br />
**[[1z91]] – BsTA <br />
**[[1z91]] – BsTA <br />
Line 307: Line 302:
**[[3vod]] – EcTA (mutant)<br />
**[[3vod]] – EcTA (mutant)<br />
**[[5h3r]] – EcTA (mutant) + DNA<br />
**[[5h3r]] – EcTA (mutant) + DNA<br />
-
**[[5eri]] – CdTA – Clostridium difficile<br />
+
**[[5eri]] – CdTA – ''Clostridium difficile''<br />
-
**[[7dvn]] – TA + effector – Paenisporosarcina<br />
+
**[[7dvn]] – TA + effector –'' Paenisporosarcina''<br />
-
**[[3u2r]] – TA – Planctopirus limnophilus<br />
+
**[[3u2r]] – TA – ''Planctopirus limnophilus''<br />
-
**[[2rdp]] – TA – Bacillus stearothermophilus<br />
+
**[[2rdp]] – TA – ''Bacillus stearothermophilus''<br />
*MerR family TA or mercuric resistance operon regulatory protein
*MerR family TA or mercuric resistance operon regulatory protein
Line 316: Line 311:
**[[3hh0]] – BcTA <br />
**[[3hh0]] – BcTA <br />
**[[3gpv]] – BtTA <br />
**[[3gpv]] – BtTA <br />
-
**[[4ua1]], [[4ua2]] – TA – Bacillus megaterium<br />
+
**[[4ua1]], [[4ua2]] – TA – ''Bacillus megaterium''<br />
**[[5crl]] – PaTA <br />
**[[5crl]] – PaTA <br />
-
**[[5gpe]] – TA – Cupriavidus metallidurans<br />
+
**[[5gpe]] – TA – ''Cupriavidus metallidurans''<br />
-
**[[3cnb]] – TA – Colwellia psychrerythraea <br />
+
**[[3cnb]] – TA – ''Colwellia psychrerythraea'' <br />
-
**[[6d90]] – HiTA – Haemophilia influenzae<br />
+
**[[6d90]] – HiTA – ''Haemophilia influenzae''<br />
**[[5d8c]] – HiTA + DNA <br />
**[[5d8c]] – HiTA + DNA <br />
**[[6xl6]], [[6xla]], [[6xlk]] – EcTA + DNA – Cryo EM<br />
**[[6xl6]], [[6xla]], [[6xlk]] – EcTA + DNA – Cryo EM<br />
Line 332: Line 327:
*AraC family TA or arabinose operon regulatory protein
*AraC family TA or arabinose operon regulatory protein
-
**[[3gra]] – PpTA – Pseudomonas putida<br />
+
**[[3gra]] – PpTA – ''Pseudomonas putida''<br />
-
**[[3cu5]] – TA – Lacnoclostridium phytofermentans<br />
+
**[[3cu5]] – TA – ''Lacnoclostridium phytofermentans''<br />
**[[5chh]] – PaTA <br />
**[[5chh]] – PaTA <br />
**[[2ara]] – EcTA <br />
**[[2ara]] – EcTA <br />
Line 344: Line 339:
**[[3kjx]], [[3e3m]] – RpTA <br />
**[[3kjx]], [[3e3m]] – RpTA <br />
-
**[[3jy6]] – TA - Lactobacillus brevis <br />
+
**[[3jy6]] – TA - ''Lactobacillus brevis'' <br />
-
**[[6chk]] – LcTA - Lactobacillus casei <br />
+
**[[6chk]] – LcTA - ''Lactobacillus casei'' <br />
**[[4rk5]], [[4rk4]] – LcTA + sugar <br />
**[[4rk5]], [[4rk4]] – LcTA + sugar <br />
**[[4rk0]], [[4rk1]] – EfTA + ribose<br />
**[[4rk0]], [[4rk1]] – EfTA + ribose<br />
**[[3h5t]] – CgTA <br />
**[[3h5t]] – CgTA <br />
**[[3kke]] – MsTA <br />
**[[3kke]] – MsTA <br />
-
**[[4rkq]], [[4rkr]] – TA - Arthrobacter<br />
+
**[[4rkq]], [[4rkr]] – TA - ''Arthrobacter''<br />
*PadR family TA
*PadR family TA
Line 364: Line 359:
*TrmB TA or tRNA (guanine-N(7)-) methyltransferase
*TrmB TA or tRNA (guanine-N(7)-) methyltransferase
-
**[[2f5t]] – TA – Thermococcus litoralis<br />
+
**[[2f5t]] – TA – ''Thermococcus litoralis''<br />
-
**[[3qph]] – PfTA + sucrose – Pyrococcus furiosus<br />
+
**[[3qph]] – PfTA + sucrose – ''Pyrococcus furiosus''<br />
*IclR TA
*IclR TA
Line 372: Line 367:
**[[2o99]], [[2o9a]] – EcTA C-terminal <br />
**[[2o99]], [[2o9a]] – EcTA C-terminal <br />
**[[1td5]] – EcTA LBD <br />
**[[1td5]] – EcTA LBD <br />
-
**[[7cuo]] – TA + hydroxybenzoate – Microbacterium hydrocarbonoxydans <br />
+
**[[7cuo]] – TA + hydroxybenzoate – ''Microbacterium hydrocarbonoxydans <br />
-
 
+
''
*BgaR TA
*BgaR TA
-
**[[6nwo]] – CpTA – Clostridium perfringens<br />
+
**[[6nwo]] – CpTA – ''Clostridium perfringens''<br />
**[[6nx3]], [[6nwj]], [[6nwm]], [[6nwh]] – CpTA + pyranose derivative<br />
**[[6nx3]], [[6nwj]], [[6nwm]], [[6nwh]] – CpTA + pyranose derivative<br />
Line 384: Line 379:
**[[3qpt]] – StTA <br />
**[[3qpt]] – StTA <br />
**[[3q5f]] – StTA + DNA <br />
**[[3q5f]] – StTA + DNA <br />
-
**[[4aih]] – YpTA – Yersinia pseudotuberculosis<br />
+
**[[4aih]] – YpTA – ''Yersinia pseudotuberculosis''<br />
**[[4aij]], [[4aik]] – YpTA + DNA <br />
**[[4aij]], [[4aik]] – YpTA + DNA <br />
- 
*CouR TA
*CouR TA
-
**[[5cyv]], [[6c28]] – RjTA + coumaroyl-CoA – Rhodococcus jostii<br />
+
**[[5cyv]], [[6c28]] – RjTA + coumaroyl-CoA –'' Rhodococcus jostii''<br />
**[[6c9t]] – RpTA <br />
**[[6c9t]] – RpTA <br />
**[[6c2s]] – RpTA + DNA <br />
**[[6c2s]] – RpTA + DNA <br />
- 
*CueR TA
*CueR TA
Line 415: Line 408:
*LmrR TA
*LmrR TA
-
**[[3f8b]], [[6i8n]] – LlTA – Lactococcus lactis<br />
+
**[[3f8b]], [[6i8n]] – LlTA – ''Lactococcus lactis''<br />
**[[3f8c]], [[3f8f]] – LlTA + drug<br />
**[[3f8c]], [[3f8f]] – LlTA + drug<br />
**[[6vwe]], [[6do0]] – LlTA + Rh complex<br />
**[[6vwe]], [[6do0]] – LlTA + Rh complex<br />
**[[6r1l]] – LlTA + Cu + phenanthroline<br />
**[[6r1l]] – LlTA + Cu + phenanthroline<br />
-
**[[4zzd] – LlTA + riboflavine<br />
+
**[[4zzd]] – LlTA + riboflavine<br />
**[[6fuu]] – LlTA + heme<br />
**[[6fuu]] – LlTA + heme<br />
Line 430: Line 423:
*HdfR TA
*HdfR TA
-
**[[6wn5]] – TA – Klebsiella pneumoniae<br />
+
**[[6wn5]] – TA – ''Klebsiella pneumoniae''<br />
*McbR TA
*McbR TA
Line 454: Line 447:
*AraR TA or arabinose metabolism transcriptional repressor
*AraR TA or arabinose metabolism transcriptional repressor
-
**[[5bs6]], [[5dd4]] – BtTA – Bacterioides thetaiotaomicron<br />
+
**[[5bs6]], [[5dd4]] – BtTA – ''Bacterioides thetaiotaomicron''<br />
**[[3tb6]] – BtTA effector-binding domain 71-362 + arabinose<br />
**[[3tb6]] – BtTA effector-binding domain 71-362 + arabinose<br />
**[[5ddg]] – BtTA + DNA<br />
**[[5ddg]] – BtTA + DNA<br />
Line 475: Line 468:
**[[4l4y]] – EcTA <br />
**[[4l4y]] – EcTA <br />
**[[4l4z]], [[4l50]], [[4l51]], [[4l5i]], [[4l5j]] – EcTA + ligand<br />
**[[4l4z]], [[4l50]], [[4l51]], [[4l5i]], [[4l5j]] – EcTA + ligand<br />
 +
 +
*TA II
 +
 +
**[[8igr]] – EcTA in transcription activation complex – Cryo EM<br />
 +
 +
*TA RAMA
 +
 +
**[[7bef]], [[7beg]] – EcTA in transcription activation complex – Cryo EM<br />
 +
 +
*PrfA TA or listeriolysin positive regulatory factor A
 +
 +
**[[1omi]], [[2beo]] – LmTA <br />
 +
**[[2bgc]], [[6qvy]], [[6qvz]], [[6qw1]], [[6qw2]] – LmTA (mutant) <br />
 +
**[[5lej]], [[5x6d]] – LmTA + DNA<br />
 +
**[[5lek]], [[6qwf]], [[6qwh]], [[6qwk]], [[6qwm]] – LmTA (mutant) + DNA <br />
 +
**[[5f1r]], [[6eut]], [[6euu]], [[6euz]], [[6ev0]], [[6exk]], [[6exl]], [[6exm]], [[6t5i]] – LmTA + inhibitor<br />
 +
**[[5lrs]], [[5x6e]] – LmTA + DNA + glutathione<br />
 +
**[[5lrr]] – LmTA + glutathione<br />
 +
**[[6hck]] – LmTA + peptide<br />
*HTH-type TA or helix-turn-helix-type
*HTH-type TA or helix-turn-helix-type
Line 481: Line 493:
**[[2uxh]] – PpTA TtgR + quercetin<br />
**[[2uxh]] – PpTA TtgR + quercetin<br />
**[[2uxi]] – PpTA TtgR + phloretin<br />
**[[2uxi]] – PpTA TtgR + phloretin<br />
-
**[[6ugl]], [[6kju]] – VcTA + pyrazine derivative<br />
+
**[[6ugl]], [[6kju]] – VcTA + pyrazine derivative<''br />
-
**[[2bv6]] – SaTA MgrA – Staphylococcus aureus<br />
+
**[[2bv6]] – SaTA MgrA –'' Staphylococcus aureus<br />
**[[5hs5]], [[5ywj]], [[6k8e]] – SaTA SarX<br />
**[[5hs5]], [[5ywj]], [[6k8e]] – SaTA SarX<br />
**[[3hrm]], [[3hse]] – SaTA SarZ <br />
**[[3hrm]], [[3hse]] – SaTA SarZ <br />
Line 494: Line 506:
**[[2hxr]] – EcTA CynR LBD <br />
**[[2hxr]] – EcTA CynR LBD <br />
**[[3hfu]] – EcTA CynR LBD + N3<br />
**[[3hfu]] – EcTA CynR LBD + N3<br />
 +
**[[8bob]] – EcTA MalT + MalY – Cryo EM <br />
**[[2gfn]] – RjTA Rha1 <br />
**[[2gfn]] – RjTA Rha1 <br />
**[[1i1g]] – PfTA LrpA <br />
**[[1i1g]] – PfTA LrpA <br />
-
**[[7cla]] – TA SkgA – Caulobacter vibrioides<br />
+
**[[7cla]] – TA SkgA – ''Caulobacter vibrioides''<br />
**[[7bzd]] – BsTA HxlR <br />
**[[7bzd]] – BsTA HxlR <br />
**[[7bze]] – BsTA HxlR (mutant)<br />
**[[7bze]] – BsTA HxlR (mutant)<br />
**[[7bzg]] – BsTA HxlR + DNA<br />
**[[7bzg]] – BsTA HxlR + DNA<br />
-
**[[7amn]], [[7amt]] – TA LuxR + DNA – Vibrio alginolyticus<br />
+
**[[7amn]], [[7amt]] – TA LuxR + DNA – ''Vibrio alginolyticus''<br />
**[[2dtz]], [[2hq5]] – SaTA QacR (mutant)<br />
**[[2dtz]], [[2hq5]] – SaTA QacR (mutant)<br />
**[[3bqz]], [[3br0]], [[3btc]], [[3btl]] – SaTA QacR (mutant) + malachite green<br />
**[[3bqz]], [[3br0]], [[3btc]], [[3btl]] – SaTA QacR (mutant) + malachite green<br />
Line 528: Line 541:
**[[4mgr]], [[4nob]], [[4tv7]] – BsTA GabR <br />
**[[4mgr]], [[4nob]], [[4tv7]] – BsTA GabR <br />
**[[6uxz]] – BsTA GabR + agonist<br />
**[[6uxz]] – BsTA GabR + agonist<br />
-
**[[5u9e]], [[5u93]] – TA RhaR regulatory domain – Bacteria latreille<br />
+
**[[5u9e]], [[5u93]] – TA RhaR regulatory domain – ''Bacteria latreille''<br />
-
**[[5z49]] – TA CmpR effector-binding domain + ribulose bisphosphate – Synechococcus elongatus<br />
+
**[[5z49]] – TA CmpR effector-binding domain + ribulose bisphosphate – ''Synechococcus elongatus''<br />
-
**[[3kos]] – CfTA AmpR effector binding domain – Citrobacter freundii<br />
+
**[[3kos]] – CfTA AmpR effector binding domain – ''Citrobacter freundii''<br />
**[[3kot]] – CfTA AmpR effector binding domain (mutant)<br />
**[[3kot]] – CfTA AmpR effector binding domain (mutant)<br />
**[[4wkm]] – CfTA AmpR effector binding domain + peptide<br />
**[[4wkm]] – CfTA AmpR effector binding domain + peptide<br />
**[[5mmh]] – PaTA AmpR effector binding domain <br />
**[[5mmh]] – PaTA AmpR effector binding domain <br />
- 
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of transcriptional activator

Updated on 01-January-2024 - For a general description of the protein see Transcriptional activator

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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