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8sge
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==KLHDC2 Kelch Domain with ligand KDRLKZ-1== | |
| - | + | <StructureSection load='8sge' size='340' side='right'caption='[[8sge]], [[Resolution|resolution]] 1.51Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8sge]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SGE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SGE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.509Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZWS:[(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic+acid'>ZWS</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sge OCA], [https://pdbe.org/8sge PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sge RCSB], [https://www.ebi.ac.uk/pdbsum/8sge PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sge ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KLDC2_HUMAN KLDC2_HUMAN] Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.<ref>PMID:11384994</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bekes M]] | ||
| + | [[Category: Digianantonio KM]] | ||
| + | [[Category: Langley DR]] | ||
| + | [[Category: Zimmerman K]] | ||
Current revision
KLHDC2 Kelch Domain with ligand KDRLKZ-1
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