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4uy7

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==Crystal structure of Histidine bound Histidine-specific methyltransferase EgtD from Mycobacterium smegmatis==
==Crystal structure of Histidine bound Histidine-specific methyltransferase EgtD from Mycobacterium smegmatis==
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<StructureSection load='4uy7' size='340' side='right' caption='[[4uy7]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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<StructureSection load='4uy7' size='340' side='right'caption='[[4uy7]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4uy7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UY7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4uy7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UY7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.306&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uy5|4uy5]], [[4uy6|4uy6]], [[4uz0|4uz0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-histidine_N(alpha)-methyltransferase L-histidine N(alpha)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.44 2.1.1.44] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uy7 OCA], [https://pdbe.org/4uy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uy7 RCSB], [https://www.ebi.ac.uk/pdbsum/4uy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uy7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uy7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uy7 RCSB], [http://www.ebi.ac.uk/pdbsum/4uy7 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EGTD_MYCS2 EGTD_MYCS2] Catalyzes the methylations of histidine to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine). Histidine and alpha-N,N-dimethylhistidine are preferred substrates.<ref>PMID:20420449</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4uy7" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Jeong, J H.]]
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[[Category: Large Structures]]
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[[Category: Kim, Y G.]]
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[[Category: Mycolicibacterium smegmatis]]
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[[Category: Antioxidant]]
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[[Category: Jeong JH]]
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[[Category: Transferase]]
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[[Category: Kim YG]]

Current revision

Crystal structure of Histidine bound Histidine-specific methyltransferase EgtD from Mycobacterium smegmatis

PDB ID 4uy7

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