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4xub
From Proteopedia
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==Crystal Structure of the bromodomain of human BAZ2B in complex with BAZ2-ICR chemical probe== | ==Crystal Structure of the bromodomain of human BAZ2B in complex with BAZ2-ICR chemical probe== | ||
| - | <StructureSection load='4xub' size='340' side='right' caption='[[4xub]], [[Resolution|resolution]] 1.98Å' scene=''> | + | <StructureSection load='4xub' size='340' side='right'caption='[[4xub]], [[Resolution|resolution]] 1.98Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xub]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUB OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4xub]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XUB FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=43D:4-{4-(1-METHYL-1H-PYRAZOL-4-YL)-1-[2-(4-METHYL-1H-1,2,3-TRIAZOL-1-YL)ETHYL]-1H-IMIDAZOL-5-YL}BENZONITRILE'>43D</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=43D:4-{4-(1-METHYL-1H-PYRAZOL-4-YL)-1-[2-(4-METHYL-1H-1,2,3-TRIAZOL-1-YL)ETHYL]-1H-IMIDAZOL-5-YL}BENZONITRILE'>43D</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xub OCA], [https://pdbe.org/4xub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xub RCSB], [https://www.ebi.ac.uk/pdbsum/4xub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xub ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4xub" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Chaikuad A]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Felletar I]] |
| - | [[Category: | + | [[Category: Knapp S]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
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Current revision
Crystal Structure of the bromodomain of human BAZ2B in complex with BAZ2-ICR chemical probe
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