This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5a1i

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:02, 10 January 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
==The structure of Humab MAT2A in complex with SAMe, Adenosine, Methionine and PPNP.==
+
==The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP.==
-
<StructureSection load='5a1i' size='340' side='right' caption='[[5a1i]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
+
<StructureSection load='5a1i' size='340' side='right'caption='[[5a1i]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5a1i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A1I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A1I FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5a1i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A1I FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PPK:(DIPHOSPHONO)AMINOPHOSPHONIC+ACID'>PPK</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a19|5a19]], [[5a1g|5a1g]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PPK:(DIPHOSPHONO)AMINOPHOSPHONIC+ACID'>PPK</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a1i OCA], [https://pdbe.org/5a1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a1i RCSB], [https://www.ebi.ac.uk/pdbsum/5a1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a1i ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a1i OCA], [http://pdbe.org/5a1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a1i RCSB], [http://www.ebi.ac.uk/pdbsum/5a1i PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN]] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
+
[https://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 5a1i" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5a1i" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Methionine adenosyltransferase]]
+
[[Category: Homo sapiens]]
-
[[Category: Antonyuk, S V]]
+
[[Category: Large Structures]]
-
[[Category: Hasnain, S S]]
+
[[Category: Antonyuk SV]]
-
[[Category: Lu, S C]]
+
[[Category: Hasnain SS]]
-
[[Category: Marina, A]]
+
[[Category: Lu SC]]
-
[[Category: Mato, J M]]
+
[[Category: Marina A]]
-
[[Category: Murray, B]]
+
[[Category: Mato JM]]
-
[[Category: Rojas, A L]]
+
[[Category: Murray B]]
-
[[Category: Cell growth]]
+
[[Category: Rojas AL]]
-
[[Category: Liver cancer]]
+
-
[[Category: Methylation]]
+
-
[[Category: Transferase]]
+

Current revision

The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP.

PDB ID 5a1i

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5a1i"
Personal tools