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5ac0

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<StructureSection load='5ac0' size='340' side='right'caption='[[5ac0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5ac0' size='340' side='right'caption='[[5ac0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ac0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_ammon_aries Ovis ammon aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AC0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ac0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AC0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K9P:1-[(1S)-1-METHYL-5-OXIDANYL-1,2-DIHYDROBENZO[E]INDOL-3-YL]HEXAN-1-ONE'>K9P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5abm|5abm]], [[5ac1|5ac1]], [[5ac2|5ac2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K9P:1-[(1S)-1-METHYL-5-OXIDANYL-1,2-DIHYDROBENZO[E]INDOL-3-YL]HEXAN-1-ONE'>K9P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Retinal_dehydrogenase Retinal dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.36 1.2.1.36] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ac0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ac0 OCA], [https://pdbe.org/5ac0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ac0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ac0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ac0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ac0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ac0 OCA], [http://pdbe.org/5ac0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ac0 RCSB], [http://www.ebi.ac.uk/pdbsum/5ac0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ac0 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AL1A1_SHEEP AL1A1_SHEEP]] Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.
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[https://www.uniprot.org/uniprot/AL1A1_SHEEP AL1A1_SHEEP] Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ovis ammon aries]]
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[[Category: Ovis aries]]
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[[Category: Retinal dehydrogenase]]
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[[Category: Blank ID]]
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[[Category: Blank, I D]]
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[[Category: Harteis S]]
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[[Category: Harteis, S]]
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[[Category: Koch MF]]
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[[Category: Koch, M F]]
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[[Category: Ochsenfeld C]]
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[[Category: Ochsenfeld, C]]
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[[Category: Pestel G]]
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[[Category: Pestel, G]]
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[[Category: Schneider S]]
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[[Category: Schneider, S]]
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[[Category: Sieber SA]]
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[[Category: Sieber, S A]]
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[[Category: Tietze LF]]
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[[Category: Tietze, L F]]
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[[Category: Aldehyde dehydrogenase activity]]
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[[Category: Oxidation-reduction process]]
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[[Category: Oxidoreductase]]
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Current revision

ovis aries Aldehyde Dehydrogenase 1A1 in complex with a duocarmycin analog

PDB ID 5ac0

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