This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5aee

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:08, 10 January 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='5aee' size='340' side='right'caption='[[5aee]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='5aee' size='340' side='right'caption='[[5aee]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5aee]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AEE FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5aee]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AEE FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NSQ:4-NITROPHENYL-ALPHA-D-SULFOQUINOVOSIDE'>NSQ</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5aed|5aed]], [[5aeg|5aeg]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NSQ:4-NITROPHENYL-ALPHA-D-SULFOQUINOVOSIDE'>NSQ</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aee OCA], [https://pdbe.org/5aee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aee RCSB], [https://www.ebi.ac.uk/pdbsum/5aee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aee ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aee OCA], [http://pdbe.org/5aee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aee RCSB], [http://www.ebi.ac.uk/pdbsum/5aee PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aee ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/YIHQ_ECOLI YIHQ_ECOLI]] Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed.<ref>PMID:15294295</ref>
+
[https://www.uniprot.org/uniprot/SQASE_ECOLI SQASE_ECOLI] Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ (PubMed:26878550). Also exhibits some alpha-glucosidase activity against alpha-glucosyl fluoride in vitro, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed (PubMed:15294295).<ref>PMID:15294295</ref> <ref>PMID:26878550</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 27:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Alpha-glucosidase]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Ecoli]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Davies, G J]]
+
[[Category: Davies GJ]]
-
[[Category: Goddard-Borger, E D]]
+
[[Category: Goddard-Borger ED]]
-
[[Category: Jin, Y]]
+
[[Category: Jin Y]]
-
[[Category: Speciale, G]]
+
[[Category: Speciale G]]
-
[[Category: Williams, S J]]
+
[[Category: Williams SJ]]
-
[[Category: Alpha-sulfoquinovosidase]]
+
-
[[Category: Gh31]]
+
-
[[Category: Hydrolase]]
+

Current revision

A bacterial protein structure in glycoside hydrolase family 31

PDB ID 5aee

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5aee"
Personal tools