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5ajs
From Proteopedia
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==Crystal structure of a coiled-coil domain from human THAP11== | ==Crystal structure of a coiled-coil domain from human THAP11== | ||
| - | <StructureSection load='5ajs' size='340' side='right' caption='[[5ajs]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='5ajs' size='340' side='right'caption='[[5ajs]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ajs]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJS OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5ajs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJS FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajs OCA], [https://pdbe.org/5ajs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajs RCSB], [https://www.ebi.ac.uk/pdbsum/5ajs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajs ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/THA11_HUMAN THA11_HUMAN] Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Cukier CD]] |
| - | [[Category: | + | [[Category: Gervais V]] |
| - | [[Category: | + | [[Category: Maveyraud L]] |
| - | [[Category: | + | [[Category: Milon A]] |
Current revision
Crystal structure of a coiled-coil domain from human THAP11
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