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5akc

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{{Large structure}}
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==MutS in complex with the N-terminal domain of MutL - crystal form 2==
==MutS in complex with the N-terminal domain of MutL - crystal form 2==
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<StructureSection load='5akc' size='340' side='right' caption='[[5akc]], [[Resolution|resolution]] 6.60&Aring;' scene=''>
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<StructureSection load='5akc' size='340' side='right'caption='[[5akc]], [[Resolution|resolution]] 6.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5akc]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AKC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5akc]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AKC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 6.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5akb|5akb]], [[5akd|5akd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5akc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5akc OCA], [http://pdbe.org/5akc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5akc RCSB], [http://www.ebi.ac.uk/pdbsum/5akc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5akc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5akc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5akc OCA], [https://pdbe.org/5akc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5akc RCSB], [https://www.ebi.ac.uk/pdbsum/5akc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5akc ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
 
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MUTS_ECOLI MUTS_ECOLI]] This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. [[http://www.uniprot.org/uniprot/MUTL_ECOLI MUTL_ECOLI]] This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA.
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[https://www.uniprot.org/uniprot/MUTS_ECOLI MUTS_ECOLI] This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5akc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5akc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Cristovao, M]]
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[[Category: Large Structures]]
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[[Category: Fish, A]]
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[[Category: Cristovao M]]
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[[Category: Friedhoff, P]]
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[[Category: Fish A]]
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[[Category: Groothuizen, F S]]
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[[Category: Friedhoff P]]
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[[Category: Hermans, N]]
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[[Category: Groothuizen FS]]
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[[Category: Lebbink, J H.G]]
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[[Category: Hermans N]]
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[[Category: Marx, A D]]
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[[Category: Lebbink JHG]]
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[[Category: Murshudov, G N]]
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[[Category: Marx AD]]
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[[Category: Nicholls, R A]]
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[[Category: Murshudov GN]]
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[[Category: Reumer, A]]
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[[Category: Nicholls RA]]
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[[Category: Sixma, T K]]
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[[Category: Reumer A]]
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[[Category: Winkler, I]]
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[[Category: Sixma TK]]
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[[Category: Winterwerp, H H.K]]
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[[Category: Winkler I]]
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[[Category: Complex]]
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[[Category: Winterwerp HHK]]
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[[Category: Crosslinking]]
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[[Category: Dna mismatch repair]]
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[[Category: Hydrolase]]
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[[Category: Sliding clamp]]
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Current revision

MutS in complex with the N-terminal domain of MutL - crystal form 2

PDB ID 5akc

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