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5bp2

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==Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 1==
==Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 1==
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<StructureSection load='5bp2' size='340' side='right' caption='[[5bp2]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='5bp2' size='340' side='right'caption='[[5bp2]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5bp2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BP2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5bp2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BP2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bp3|5bp3]], [[5bp4|5bp4]], [[5bp5|5bp5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bp2 OCA], [http://pdbe.org/5bp2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bp2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bp2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bp2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bp2 OCA], [https://pdbe.org/5bp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bp2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bp2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PKS5_MYCS2 PKS5_MYCS2]] Polyketide synthase involved in the biosynthesis of 2,4-dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis.<ref>PMID:19181796</ref>
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[https://www.uniprot.org/uniprot/PKS5_MYCS2 PKS5_MYCS2] Polyketide synthase involved in the biosynthesis of 2,4-dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis.<ref>PMID:19181796</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Herbst, D A]]
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[[Category: Large Structures]]
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[[Category: Jakob, P R]]
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[[Category: Mycolicibacterium smegmatis MC2 155]]
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[[Category: Maier, T]]
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[[Category: Herbst DA]]
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[[Category: Zaehringer, F]]
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[[Category: Jakob PR]]
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[[Category: Dehydratase]]
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[[Category: Maier T]]
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[[Category: Dh]]
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[[Category: Zaehringer F]]
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[[Category: Lyase]]
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[[Category: Pk]]
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[[Category: Polyketide]]
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Current revision

Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 1

PDB ID 5bp2

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