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5n3v

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<StructureSection load='5n3v' size='340' side='right'caption='[[5n3v]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
<StructureSection load='5n3v' size='340' side='right'caption='[[5n3v]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5n3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N3V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5N3V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5n3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N3V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8L5:~{N}-[(2~{S})-1-(aminomethylamino)-4-methyl-1-oxidanylidene-pentan-2-yl]-(phenylmethoxycarbonylaminomethyl)phosphonamidic+acid;hydrogen'>8L5</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8L5:~{N}-[(2~{S})-1-(aminomethylamino)-4-methyl-1-oxidanylidene-pentan-2-yl]-(phenylmethoxycarbonylaminomethyl)phosphonamidic+acid;hydrogen'>8L5</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5n3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n3v OCA], [http://pdbe.org/5n3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n3v RCSB], [http://www.ebi.ac.uk/pdbsum/5n3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n3v ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n3v OCA], [https://pdbe.org/5n3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n3v RCSB], [https://www.ebi.ac.uk/pdbsum/5n3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n3v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
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[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5n3v" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5n3v" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thermolysin]]
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[[Category: Cramer J]]
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[[Category: Cramer, J]]
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[[Category: Heine A]]
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[[Category: Heine, A]]
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[[Category: Klebe G]]
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[[Category: Klebe, G]]
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[[Category: Krimmer SG]]
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[[Category: Krimmer, S G]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Phosphonamidate]]
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[[Category: Protease]]
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Current revision

Thermolysin in complex with inhibitor JC292

PDB ID 5n3v

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