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2xln
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==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor== | ==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor== | ||
| - | <StructureSection load='2xln' size='340' side='right' caption='[[2xln]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='2xln' size='340' side='right'caption='[[2xln]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xln]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xln]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_sp._R39 Actinomadura sp. R39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XLN FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EWA:[(1S)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}ETHYL]BORONIC+ACID'>EWA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EWA:[(1S)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}ETHYL]BORONIC+ACID'>EWA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xln OCA], [https://pdbe.org/2xln PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xln RCSB], [https://www.ebi.ac.uk/pdbsum/2xln PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xln ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2xln" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Penicillin-binding protein|Penicillin-binding protein]] | + | *[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]] |
| + | *[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Actinomadura sp.]] | + | [[Category: Actinomadura sp. R39]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Charlier | + | [[Category: Charlier P]] |
| - | [[Category: Herman | + | [[Category: Herman R]] |
| - | [[Category: Kerff | + | [[Category: Kerff F]] |
| - | [[Category: Rocaboy | + | [[Category: Rocaboy M]] |
| - | [[Category: Sauvage | + | [[Category: Sauvage E]] |
| - | + | ||
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Current revision
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor
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