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3udu

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==Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni==
==Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni==
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<StructureSection load='3udu' size='340' side='right' caption='[[3udu]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='3udu' size='340' side='right'caption='[[3udu]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3udu]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"campylobacter_fetus_subsp._jejuni"_smibert_1974 "campylobacter fetus subsp. jejuni" smibert 1974]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UDU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3udu]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UDU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3udo|3udo]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">leuB, Cj1718c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=197 "Campylobacter fetus subsp. jejuni" Smibert 1974])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3udu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3udu OCA], [https://pdbe.org/3udu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3udu RCSB], [https://www.ebi.ac.uk/pdbsum/3udu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3udu ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3udu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3udu OCA], [http://pdbe.org/3udu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3udu RCSB], [http://www.ebi.ac.uk/pdbsum/3udu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3udu ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LEU3_CAMJE LEU3_CAMJE]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
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[https://www.uniprot.org/uniprot/LEU3_CAMJE LEU3_CAMJE] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
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==See Also==
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*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Campylobacter fetus subsp. jejuni smibert 1974]]
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[[Category: Campylobacter jejuni]]
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[[Category: 3-isopropylmalate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Chruszcz M]]
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[[Category: Chruszcz, M]]
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[[Category: Grimshaw S]]
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[[Category: Grimshaw, S]]
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[[Category: Minor W]]
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[[Category: Minor, W]]
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[[Category: Onopriyenko O]]
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[[Category: Onopriyenko, O]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A]]
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[[Category: Tkaczuk KL]]
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[[Category: Tkaczuk, K L]]
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[[Category: Csgid]]
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[[Category: Oxidoreductase]]
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[[Category: Putative isopropylmalate dehydrogenase]]
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Current revision

Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni

PDB ID 3udu

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