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6htk

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==X-ray structure of the tryptophan lyase NosL in complex with (R)-(+)-indoline-2-carboxylate==
==X-ray structure of the tryptophan lyase NosL in complex with (R)-(+)-indoline-2-carboxylate==
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<StructureSection load='6htk' size='340' side='right' caption='[[6htk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='6htk' size='340' side='right'caption='[[6htk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6htk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_actuosus"_pinnert_et_al. "streptomyces actuosus" pinnert et al.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HTK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HTK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6htk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_actuosus Streptomyces actuosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HTK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ICB:1H-INDOLE-2-CARBOXYLIC+ACID'>ICB</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nosL, nocL, DMT42_23170 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1885 "Streptomyces actuosus" Pinnert et al.])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ICB:1H-INDOLE-2-CARBOXYLIC+ACID'>ICB</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6htk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6htk OCA], [http://pdbe.org/6htk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6htk RCSB], [http://www.ebi.ac.uk/pdbsum/6htk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6htk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6htk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6htk OCA], [https://pdbe.org/6htk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6htk RCSB], [https://www.ebi.ac.uk/pdbsum/6htk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6htk ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C6FX51_STRAS C6FX51_STRAS]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptomyces actuosus pinnert et al]]
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[[Category: Large Structures]]
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[[Category: Amara, P]]
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[[Category: Streptomyces actuosus]]
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[[Category: Bella, M]]
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[[Category: Amara P]]
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[[Category: Gambarelli, S]]
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[[Category: Bella M]]
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[[Category: Martin, L]]
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[[Category: Gambarelli S]]
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[[Category: Mouesca, J M]]
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[[Category: Martin L]]
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[[Category: Nicolet, Y]]
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[[Category: Mouesca JM]]
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[[Category: Saragaglia, C]]
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[[Category: Nicolet Y]]
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[[Category: Antibiotic]]
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[[Category: Saragaglia C]]
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[[Category: Fes cluster]]
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[[Category: Nosiheptide]]
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[[Category: Radical sam]]
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Current revision

X-ray structure of the tryptophan lyase NosL in complex with (R)-(+)-indoline-2-carboxylate

PDB ID 6htk

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