This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6qa5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6qa5 is ON HOLD Authors: Chowdhury, R., Pfeffer, I., Schofield, C.J. Description: Aspartyl/Asparaginyl beta-hydroxylase (AspH) H679A in the apo for...) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Aspartyl/Asparaginyl beta-hydroxylase (AspH) H679A in the apo form== | |
| + | <StructureSection load='6qa5' size='340' side='right'caption='[[6qa5]], [[Resolution|resolution]] 2.66Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6qa5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QA5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.655Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qa5 OCA], [https://pdbe.org/6qa5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qa5 RCSB], [https://www.ebi.ac.uk/pdbsum/6qa5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qa5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ASPH_HUMAN ASPH_HUMAN] Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.<ref>PMID:22586105</ref> Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.<ref>PMID:22586105</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Hydroxylases 3D structures|Hydroxylases 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Chowdhury | + | __TOC__ |
| - | [[Category: Pfeffer | + | </StructureSection> |
| - | [[Category: Schofield | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chowdhury R]] | ||
| + | [[Category: Pfeffer I]] | ||
| + | [[Category: Schofield CJ]] | ||
Current revision
Aspartyl/Asparaginyl beta-hydroxylase (AspH) H679A in the apo form
| |||||||||||
