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3iz0

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<SX load='3iz0' size='340' side='right' viewer='molstar' caption='[[3iz0]], [[Resolution|resolution]] 8.60&Aring;' scene=''>
<SX load='3iz0' size='340' side='right' viewer='molstar' caption='[[3iz0]], [[Resolution|resolution]] 8.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3iz0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3iz0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZ0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NDC80 SPC25, SPBC25, AD024 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUF2, RP11-77M5.2-004, SPC24 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iz0 OCA], [https://pdbe.org/3iz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iz0 RCSB], [https://www.ebi.ac.uk/pdbsum/3iz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iz0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iz0 OCA], [https://pdbe.org/3iz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iz0 RCSB], [https://www.ebi.ac.uk/pdbsum/3iz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iz0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Alushin, G M]]
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[[Category: Alushin GM]]
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[[Category: Ball, D A]]
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[[Category: Ball DA]]
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[[Category: Grigorieff, N]]
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[[Category: Grigorieff N]]
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[[Category: Musacchio, A]]
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[[Category: Musacchio A]]
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[[Category: Nogales, E]]
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[[Category: Nogales E]]
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[[Category: Pasqualato, S]]
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[[Category: Pasqualato S]]
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[[Category: Ramey, V H]]
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[[Category: Ramey VH]]
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[[Category: Calponin homology domain]]
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[[Category: Cell cycle]]
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[[Category: Hec1]]
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[[Category: Kinetochore]]
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[[Category: Microtubule]]
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[[Category: Mitosis]]
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[[Category: Ndc80]]
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[[Category: Nuf2]]
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[[Category: Tubulin]]
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Revision as of 14:11, 24 January 2024

Human Ndc80 Bonsai Decorated Microtubule

3iz0, resolution 8.60Å

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