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8i3y
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8i3y is ON HOLD Authors: Mochizuki, K., Inaoka, D.K., Fukuda, K., Kurasawa, H., Iyoda, K., Nakai, U., Harada, S., Balogun, E.O., Mazet, M., Millerio...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA.== | |
| - | + | <StructureSection load='8i3y' size='340' side='right'caption='[[8i3y]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8i3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I3Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SCA:SUCCINYL-COENZYME+A'>SCA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i3y OCA], [https://pdbe.org/8i3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i3y RCSB], [https://www.ebi.ac.uk/pdbsum/8i3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i3y ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/Q386P1_TRYB2 Q386P1_TRYB2] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.[PIRNR:PIRNR000858] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Trypanosoma brucei brucei TREU927]] |
| - | [[Category: | + | [[Category: Balogun EO]] |
| - | [[Category: | + | [[Category: Boshart M]] |
| - | [[Category: | + | [[Category: Bringaud F]] |
| - | [[Category: | + | [[Category: Fukuda K]] |
| - | [[Category: | + | [[Category: Harada S]] |
| - | [[Category: Mochizuki | + | [[Category: Hirayama K]] |
| - | [[Category: | + | [[Category: Inaoka DK]] |
| + | [[Category: Iyoda K]] | ||
| + | [[Category: Kita K]] | ||
| + | [[Category: Kurasawa H]] | ||
| + | [[Category: Mazet M]] | ||
| + | [[Category: Millerioux Y]] | ||
| + | [[Category: Mochizuki K]] | ||
| + | [[Category: Nakai U]] | ||
| + | [[Category: Shiba T]] | ||
Current revision
Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA.
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Categories: Large Structures | Trypanosoma brucei brucei TREU927 | Balogun EO | Boshart M | Bringaud F | Fukuda K | Harada S | Hirayama K | Inaoka DK | Iyoda K | Kita K | Kurasawa H | Mazet M | Millerioux Y | Mochizuki K | Nakai U | Shiba T
