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5nuk

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==Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP)==
==Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP)==
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<StructureSection load='5nuk' size='340' side='right' caption='[[5nuk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='5nuk' size='340' side='right'caption='[[5nuk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5nuk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NUK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5nuk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NUK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=Z80:3-(2-CHLORO-10H-PHENOTHIAZIN-10-YL)-N,N-DIMETHYLPROPAN-1-AMINE'>Z80</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LGB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=Z80:3-(2-CHLORO-10H-PHENOTHIAZIN-10-YL)-N,N-DIMETHYLPROPAN-1-AMINE'>Z80</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nuk OCA], [http://pdbe.org/5nuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nuk RCSB], [http://www.ebi.ac.uk/pdbsum/5nuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nuk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nuk OCA], [https://pdbe.org/5nuk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nuk RCSB], [https://www.ebi.ac.uk/pdbsum/5nuk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nuk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN]] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
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[https://www.uniprot.org/uniprot/LACB_BOVIN LACB_BOVIN] Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5nuk" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5nuk" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Beta-lactoglobulin 3D structures|Beta-lactoglobulin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
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[[Category: Bonarek, P]]
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[[Category: Large Structures]]
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[[Category: Lazinska, I]]
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[[Category: Bonarek P]]
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[[Category: Lewinski, K]]
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[[Category: Lazinska I]]
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[[Category: Loch, J I]]
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[[Category: Lewinski K]]
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[[Category: Szydlowska, J]]
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[[Category: Loch JI]]
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[[Category: Tworzydlo, M]]
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[[Category: Szydlowska J]]
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[[Category: Beta-lactoglobulin]]
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[[Category: Tworzydlo M]]
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[[Category: Chlorpromazine]]
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[[Category: Complex]]
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[[Category: Lipocalin]]
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[[Category: Mutation]]
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[[Category: Transport protein]]
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Current revision

Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP)

PDB ID 5nuk

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