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6enz

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==Crystal structure of mouse GADL1==
==Crystal structure of mouse GADL1==
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<StructureSection load='6enz' size='340' side='right' caption='[[6enz]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='6enz' size='340' side='right'caption='[[6enz]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6enz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ENZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ENZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6enz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ENZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ENZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Gadl1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6enz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6enz OCA], [http://pdbe.org/6enz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6enz RCSB], [http://www.ebi.ac.uk/pdbsum/6enz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6enz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6enz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6enz OCA], [https://pdbe.org/6enz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6enz RCSB], [https://www.ebi.ac.uk/pdbsum/6enz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6enz ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GADL1_MOUSE GADL1_MOUSE] Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is L-aspartate. Does not exhibit any decarboxylation activity toward glutamate.<ref>PMID:26327310</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Haavik, J]]
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[[Category: Mus musculus]]
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[[Category: Kursula, P]]
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[[Category: Haavik J]]
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[[Category: Luan, W]]
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[[Category: Kursula P]]
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[[Category: Mahootchi, E]]
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[[Category: Luan W]]
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[[Category: Raasakka, A]]
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[[Category: Mahootchi E]]
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[[Category: Winge, I]]
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[[Category: Raasakka A]]
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[[Category: Decarboxylase]]
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[[Category: Winge I]]
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[[Category: Homodimer]]
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[[Category: Lyase]]
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[[Category: Pyridoxal phosphate]]
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Current revision

Crystal structure of mouse GADL1

PDB ID 6enz

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