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7alx
From Proteopedia
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==Sav-SOD: Chimeric Streptavidin-cSOD as Host for Artificial Metalloenzymes== | ==Sav-SOD: Chimeric Streptavidin-cSOD as Host for Artificial Metalloenzymes== | ||
| - | <StructureSection load='7alx' size='340' side='right'caption='[[7alx]]' scene=''> | + | <StructureSection load='7alx' size='340' side='right'caption='[[7alx]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ALX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ALX FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7alx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_variant_bovis_AF2122/97 Mycobacterium tuberculosis variant bovis AF2122/97] and [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ALX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ALX FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7alx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7alx OCA], [https://pdbe.org/7alx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7alx RCSB], [https://www.ebi.ac.uk/pdbsum/7alx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7alx ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UFW:((4S)-1,3-dimesityl-4-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)methyl)imidazolidin-2-yl)gold'>UFW</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7alx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7alx OCA], [https://pdbe.org/7alx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7alx RCSB], [https://www.ebi.ac.uk/pdbsum/7alx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7alx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).[https://www.uniprot.org/uniprot/SODC_MYCBO SODC_MYCBO] Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis variant bovis AF2122/97]] | ||
| + | [[Category: Streptomyces avidinii]] | ||
[[Category: Christoffel F]] | [[Category: Christoffel F]] | ||
[[Category: Igareta NV]] | [[Category: Igareta NV]] | ||
[[Category: Peterson RL]] | [[Category: Peterson RL]] | ||
[[Category: Ward TR]] | [[Category: Ward TR]] | ||
Current revision
Sav-SOD: Chimeric Streptavidin-cSOD as Host for Artificial Metalloenzymes
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