This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7ngy
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7ngy is ON HOLD Authors: Tomlinson, C.W.E., Tatum, N.J., Pohl, E. Description: Mycobacterium tuberculosis transcriptional regulator EthR with bound...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound== | |
| + | <StructureSection load='7ngy' size='340' side='right'caption='[[7ngy]], [[Resolution|resolution]] 1.27Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ngy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGY FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.27Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UBN:4-methyl-~{N}-[(~{E})-oct-5-enyl]piperidine-1-carboxamide'>UBN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngy OCA], [https://pdbe.org/7ngy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngy RCSB], [https://www.ebi.ac.uk/pdbsum/7ngy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Pohl | + | __TOC__ |
| - | [[Category: Tatum | + | </StructureSection> |
| - | [[Category: Tomlinson | + | [[Category: Large Structures]] |
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Pohl E]] | ||
| + | [[Category: Tatum NJ]] | ||
| + | [[Category: Tomlinson CWE]] | ||
Current revision
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
| |||||||||||
