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7ou8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7ou8 is ON HOLD Authors: Males, A., Davies, G.J., Gonzalez-Cuesta, M., Mellet, C.O., Fernandez, J.M.G., Sidhu, P., Ashmus, R., Busmann, J., Vocadlo,...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Human O-GlcNAc hydrolase in complex with DNJNAc-thiazolidines== | |
| + | <StructureSection load='7ou8' size='340' side='right'caption='[[7ou8]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ou8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OU8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1XI:~{N}-[(3~{Z},6~{S},7~{R},8~{R},8~{a}~{S})-7,8-bis(oxidanyl)-3-(phenylmethyl)imino-1,5,6,7,8,8~{a}-hexahydro-[1,3]thiazolo[3,4-a]pyridin-6-yl]ethanamide'>1XI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ou8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ou8 OCA], [https://pdbe.org/7ou8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ou8 RCSB], [https://www.ebi.ac.uk/pdbsum/7ou8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ou8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OGA_BACTN OGA_BACTN] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. | ||
| - | + | ==See Also== | |
| - | + | *[[O-GlcNAcase|O-GlcNAcase]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Bacteroides thetaiotaomicron VPI-5482]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ashmus R]] |
| - | [[Category: | + | [[Category: Busmann J]] |
| - | [[Category: | + | [[Category: Davies GJ]] |
| - | [[Category: | + | [[Category: Fernandez JMG]] |
| - | [[Category: | + | [[Category: Foster L]] |
| - | [[Category: Mellet | + | [[Category: Gonzalez-Cuesta M]] |
| - | [[Category: | + | [[Category: Males A]] |
| - | [[Category: | + | [[Category: Mellet CO]] |
| + | [[Category: Sidhu P]] | ||
| + | [[Category: Vocadlo DJ]] | ||
Current revision
Human O-GlcNAc hydrolase in complex with DNJNAc-thiazolidines
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