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2yl8
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2yl8' size='340' side='right' caption='[[2yl8]], [[Resolution|resolution]] 1.75Å' scene=''> | + | ==Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis== |
| + | <StructureSection load='2yl8' size='340' side='right'caption='[[2yl8]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yl8]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2yl8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YL8 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand= | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yl8 OCA], [https://pdbe.org/2yl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yl8 RCSB], [https://www.ebi.ac.uk/pdbsum/2yl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yl8 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/STRH_STRPN STRH_STRPN] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2yl8" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]] | *[[Beta-Hexosaminidase|Beta-Hexosaminidase]] | ||
| + | *[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]] | ||
| + | *[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Streptococcus pneumoniae]] | + | [[Category: Streptococcus pneumoniae TIGR4]] |
| - | [[Category: Abbott | + | [[Category: Abbott DW]] |
| - | [[Category: Boraston | + | [[Category: Boraston AB]] |
| - | [[Category: Dalia | + | [[Category: Dalia AB]] |
| - | [[Category: Deng | + | [[Category: Deng L]] |
| - | [[Category: Fairbanks | + | [[Category: Fairbanks AJ]] |
| - | [[Category: Higgins | + | [[Category: Higgins MA]] |
| - | [[Category: Parsons | + | [[Category: Parsons TB]] |
| - | [[Category: Pluvinage | + | [[Category: Pluvinage B]] |
| - | [[Category: Robb | + | [[Category: Robb C]] |
| - | [[Category: Vocadlo | + | [[Category: Vocadlo DJ]] |
| - | [[Category: Weiser | + | [[Category: Weiser JN]] |
| - | + | ||
Current revision
Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis
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