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5qbw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5qbw is ON HOLD Authors: Yang, H., Shao, C., Burley, S. Description: Ligand binding to Cathepsin S Category: Unreleased Structures [[Category: ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human Cathepsin-S with bound ligand== | |
| + | <StructureSection load='5qbw' size='340' side='right'caption='[[5qbw]], [[Resolution|resolution]] 3.01Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5qbw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QBW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B8S:N-{[2-chloro-5-(2-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-3-oxo-2,3-dihydropyridazin-4-yl)phenyl]methyl}-4-fluorobenzamide'>B8S</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qbw OCA], [https://pdbe.org/5qbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qbw RCSB], [https://www.ebi.ac.uk/pdbsum/5qbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qbw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | ||
| - | + | ==See Also== | |
| - | + | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Burley | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Shao | + | [[Category: Ameriks MK]] |
| + | [[Category: Bembenek SD]] | ||
| + | [[Category: Burley SK]] | ||
| + | [[Category: Mirzadegan T]] | ||
| + | [[Category: Shao C]] | ||
| + | [[Category: Yang H]] | ||
Current revision
Crystal structure of human Cathepsin-S with bound ligand
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Categories: Homo sapiens | Large Structures | Ameriks MK | Bembenek SD | Burley SK | Mirzadegan T | Shao C | Yang H
