This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
190d
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of a four-stranded intercalated DNA: d(C4)== | ==Crystal structure of a four-stranded intercalated DNA: d(C4)== | ||
| - | <StructureSection load='190d' size='340' side='right' caption='[[190d]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='190d' size='340' side='right'caption='[[190d]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[190d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[190d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=190D FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=190d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=190d OCA], [https://pdbe.org/190d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=190d RCSB], [https://www.ebi.ac.uk/pdbsum/190d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=190d ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The crystal structure of d(C4) solved at 2.3-A resolution reveals a four-stranded molecule composed of two interdigitated or intercalated duplexes. The duplexes are held together by hemiprotonated cytosine-cytosine base pairs and are parallel stranded, but the two duplexes point in opposite directions. The molecule has a slow right-handed twist of 12.4 degrees between covalently linked cytosine base pairs, and the base stacking distance is 3.1 A. This is in general agreement with the NMR studies. A biological role for DNA in this conformation is suggested. | ||
| - | |||
| - | Crystal structure of a four-stranded intercalated DNA: d(C4).,Chen L, Cai L, Zhang X, Rich A Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:7947764<ref>PMID:7947764</ref> | ||
| - | |||
| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cai | + | [[Category: Large Structures]] |
| - | [[Category: Chen | + | [[Category: Cai L]] |
| - | [[Category: Rich | + | [[Category: Chen L]] |
| - | [[Category: Zhang | + | [[Category: Rich A]] |
| - | + | [[Category: Zhang X]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of a four-stranded intercalated DNA: d(C4)
| |||||||||||
Categories: Large Structures | Cai L | Chen L | Rich A | Zhang X
