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1a1h

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{{Seed}}
 
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[[Image:1a1h.png|left|200px]]
 
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<!--
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==QGSR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)==
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The line below this paragraph, containing "STRUCTURE_1a1h", creates the "Structure Box" on the page.
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<StructureSection load='1a1h' size='340' side='right'caption='[[1a1h]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1a1h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A1H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1a1h| PDB=1a1h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a1h OCA], [https://pdbe.org/1a1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a1h RCSB], [https://www.ebi.ac.uk/pdbsum/1a1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a1h ProSAT]</span></td></tr>
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</table>
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===QGSR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)===
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== Function ==
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[https://www.uniprot.org/uniprot/EGR1_MOUSE EGR1_MOUSE] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_9562555}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9562555 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/1a1h_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9562555}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1A1H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A1H OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a1h ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition., Elrod-Erickson M, Benson TE, Pabo CO, Structure. 1998 Apr 15;6(4):451-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9562555 9562555]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Benson TE]]
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[[Category: Benson, T E.]]
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[[Category: Elrod-Erickson M]]
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[[Category: Elrod-Erickson, M.]]
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[[Category: Pabo CO]]
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[[Category: Pabo, C O.]]
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[[Category: Dna-binding protein]]
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[[Category: Zinc finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:47:12 2008''
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Current revision

QGSR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)

PDB ID 1a1h

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