1a8h
From Proteopedia
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- | [[Image:1a8h.png|left|200px]] | ||
- | + | ==METHIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS== | |
- | + | <StructureSection load='1a8h' size='340' side='right'caption='[[1a8h]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1a8h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A8H FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a8h OCA], [https://pdbe.org/1a8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a8h RCSB], [https://www.ebi.ac.uk/pdbsum/1a8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a8h ProSAT], [https://www.topsan.org/Proteins/RSGI/1a8h TOPSAN]</span></td></tr> |
- | [[1a8h]] is a 1 chain structure | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a8/1a8h_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a8h ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Aminoacyl tRNA | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
- | [[Category: | + | [[Category: Thermus thermophilus HB8]] |
- | [[Category: Thermus thermophilus]] | + | [[Category: Giege R]] |
- | [[Category: Giege | + | [[Category: Konno M]] |
- | [[Category: Konno | + | [[Category: Kuwabara S]] |
- | [[Category: Kuwabara | + | [[Category: Lober B]] |
- | [[Category: Lober | + | [[Category: Moras D]] |
- | [[Category: Moras | + | [[Category: Nureki O]] |
- | [[Category: Nureki | + | [[Category: Sugiura I]] |
- | + | [[Category: Ugaji Y]] | |
- | [[Category: Sugiura | + | [[Category: Yokoyama S]] |
- | [[Category: Ugaji | + | |
- | [[Category: Yokoyama | + | |
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Current revision
METHIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS
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Categories: Large Structures | Thermus thermophilus HB8 | Giege R | Konno M | Kuwabara S | Lober B | Moras D | Nureki O | Sugiura I | Ugaji Y | Yokoyama S