This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1a9c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1a9c" size="450" color="white" frame="true" align="right" spinBox="true" caption="1a9c, resolution 2.9&Aring;" /> '''GTP CYCLOHYDROLASE I ...)
Current revision (06:28, 7 February 2024) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1a9c.gif|left|200px]]<br /><applet load="1a9c" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1a9c, resolution 2.9&Aring;" />
 
-
'''GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP'''<br />
 
-
==About this Structure==
+
==GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP==
-
1A9C is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with GTP as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A9C OCA].
+
<StructureSection load='1a9c' size='340' side='right'caption='[[1a9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
[[Category: Escherichia coli]]
+
== Structural highlights ==
-
[[Category: GTP cyclohydrolase I]]
+
<table><tr><td colspan='2'>[[1a9c]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A9C FirstGlance]. <br>
-
[[Category: Single protein]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
[[Category: Auerbach, G.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
-
[[Category: Bacher, A.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a9c OCA], [https://pdbe.org/1a9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a9c RCSB], [https://www.ebi.ac.uk/pdbsum/1a9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a9c ProSAT]</span></td></tr>
-
[[Category: Bracher, A.]]
+
</table>
-
[[Category: Huber, R.]]
+
== Function ==
-
[[Category: Nar, H.]]
+
[https://www.uniprot.org/uniprot/GCH1_ECOLI GCH1_ECOLI]
-
[[Category: GTP]]
+
== Evolutionary Conservation ==
-
[[Category: gtp]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: hydrolase]]
+
Check<jmol>
-
[[Category: pterine synthesis]]
+
<jmolCheckbox>
-
[[Category: purine hydrolysis]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a9/1a9c_consurf.spt"</scriptWhenChecked>
-
[[Category: tetrahydrobiopterin]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a9c ConSurf].
 +
<div style="clear:both"></div>
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 10:41:57 2007''
+
==See Also==
 +
*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Escherichia coli]]
 +
[[Category: Large Structures]]
 +
[[Category: Auerbach G]]
 +
[[Category: Bacher A]]
 +
[[Category: Bracher A]]
 +
[[Category: Huber R]]
 +
[[Category: Nar H]]

Current revision

GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP

PDB ID 1a9c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools