1ae1

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{{Seed}}
 
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[[Image:1ae1.png|left|200px]]
 
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==TROPINONE REDUCTASE-I COMPLEX WITH NADP==
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The line below this paragraph, containing "STRUCTURE_1ae1", creates the "Structure Box" on the page.
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<StructureSection load='1ae1' size='340' side='right'caption='[[1ae1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ae1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Datura_stramonium Datura stramonium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AE1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_1ae1| PDB=1ae1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ae1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ae1 OCA], [https://pdbe.org/1ae1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ae1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ae1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ae1 ProSAT]</span></td></tr>
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</table>
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===TROPINONE REDUCTASE-I COMPLEX WITH NADP===
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== Function ==
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[https://www.uniprot.org/uniprot/TRN1_DATST TRN1_DATST] Catalyzes the stereospecific reduction of tropinone to tropine.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_9560196}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9560196 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/1ae1_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9560196}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1AE1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Datura_stramonium Datura stramonium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AE1 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ae1 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold., Nakajima K, Yamashita A, Akama H, Nakatsu T, Kato H, Hashimoto T, Oda J, Yamada Y, Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4876-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9560196 9560196]
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</StructureSection>
[[Category: Datura stramonium]]
[[Category: Datura stramonium]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Tropinone reductase II]]
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[[Category: Akama H]]
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[[Category: Akama, H.]]
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[[Category: Hashimoto T]]
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[[Category: Hashimoto, T.]]
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[[Category: Kato H]]
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[[Category: Kato, H.]]
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[[Category: Nakajima K]]
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[[Category: Nakajima, K.]]
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[[Category: Nakatsu T]]
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[[Category: Nakatsu, T.]]
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[[Category: Oda J]]
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[[Category: Oda, J.]]
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[[Category: Yamada Y]]
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[[Category: Yamada, Y.]]
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[[Category: Yamashita A]]
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[[Category: Yamashita, A.]]
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[[Category: Oxidoreductase]]
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[[Category: Reduction of tropinone to tropine]]
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[[Category: Short-chain dehydrogenase]]
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[[Category: Tropane alkaloid biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:39:06 2008''
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Current revision

TROPINONE REDUCTASE-I COMPLEX WITH NADP

PDB ID 1ae1

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