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1bc2

From Proteopedia

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{{Seed}}
 
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[[Image:1bc2.png|left|200px]]
 
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==ZN-DEPENDENT METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS==
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The line below this paragraph, containing "STRUCTURE_1bc2", creates the "Structure Box" on the page.
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<StructureSection load='1bc2' size='340' side='right'caption='[[1bc2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bc2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BC2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1bc2| PDB=1bc2 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bc2 OCA], [https://pdbe.org/1bc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bc2 RCSB], [https://www.ebi.ac.uk/pdbsum/1bc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bc2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/1bc2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bc2 ConSurf].
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<div style="clear:both"></div>
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===ZN-DEPENDENT METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS===
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9730812}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9730812 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9730812}}
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==About this Structure==
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1BC2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BC2 OCA].
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==Reference==
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Crystal structure of the zinc-dependent beta-lactamase from Bacillus cereus at 1.9 A resolution: binuclear active site with features of a mononuclear enzyme., Fabiane SM, Sohi MK, Wan T, Payne DJ, Bateson JH, Mitchell T, Sutton BJ, Biochemistry. 1998 Sep 8;37(36):12404-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9730812 9730812]
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[[Category: Bacillus cereus]]
[[Category: Bacillus cereus]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Fabiane SM]]
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[[Category: Fabiane, S M.]]
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[[Category: Sutton BJ]]
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[[Category: Sutton, B J.]]
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[[Category: Antibiotic resistance]]
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[[Category: Hydrolase]]
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[[Category: Metallo beta-lactamase]]
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[[Category: Penicillinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 18:48:02 2008''
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Current revision

ZN-DEPENDENT METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS

PDB ID 1bc2

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