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1bf6

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{{Seed}}
 
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[[Image:1bf6.png|left|200px]]
 
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<!--
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==PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI==
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The line below this paragraph, containing "STRUCTURE_1bf6", creates the "Structure Box" on the page.
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<StructureSection load='1bf6' size='340' side='right'caption='[[1bf6]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bf6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BF6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1bf6| PDB=1bf6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bf6 OCA], [https://pdbe.org/1bf6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bf6 RCSB], [https://www.ebi.ac.uk/pdbsum/1bf6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bf6 ProSAT]</span></td></tr>
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</table>
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===PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI===
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== Function ==
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[https://www.uniprot.org/uniprot/PHP_ECOLI PHP_ECOLI] Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates: P-nitrophenyl acetate, L-alanine nitroanilide, P-nitrophenyl sulfate, bis(P-nitrophenyl) phosphate, paraoxon, and P-nitrophenyl phosphate. No enzymatic activity was detected with any of these nonspecific substrates.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_9548740}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9548740 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bf/1bf6_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9548740}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1BF6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BF6 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bf6 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family., Buchbinder JL, Stephenson RC, Dresser MJ, Pitera JW, Scanlan TS, Fletterick RJ, Biochemistry. 1998 Apr 14;37(15):5096-106. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9548740 9548740]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Buchbinder, J L.]]
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[[Category: Buchbinder JL]]
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[[Category: Fletterick, R J.]]
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[[Category: Fletterick RJ]]
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[[Category: Scanlan, T S.]]
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[[Category: Scanlan TS]]
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[[Category: Stephenson, R C.]]
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[[Category: Stephenson RC]]
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[[Category: Hypothetical protein]]
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[[Category: Phosphotriesterase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:01:26 2008''
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Current revision

PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI

PDB ID 1bf6

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