1bsd

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[[Image:1bsd.png|left|200px]]
 
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{{STRUCTURE_1bsd| PDB=1bsd | SCENE= }}
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==CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE==
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<StructureSection load='1bsd' size='340' side='right'caption='[[1bsd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bsd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BSD FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8254677}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bsd OCA], [https://pdbe.org/1bsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bsd RCSB], [https://www.ebi.ac.uk/pdbsum/1bsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bsd ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1bsd]] is a 3 chain structure of [[Barnase]] and [[Ribonuclease]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSD OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/RNBR_BACAM RNBR_BACAM] Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/1bsd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bsd ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Barnase|Barnase]]
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*[[Barnase 3D structures|Barnase 3D structures]]
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008254677</ref><references group="xtra"/>
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[[Category: Bacillus amyloliquefaciens]]
[[Category: Bacillus amyloliquefaciens]]
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[[Category: Buckle, A M.]]
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[[Category: Large Structures]]
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[[Category: Fersht, A R.]]
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[[Category: Buckle AM]]
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[[Category: Henrick, K.]]
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[[Category: Fersht AR]]
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[[Category: Endonuclease]]
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[[Category: Henrick K]]

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CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE

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