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1bsg

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[[Image:1bsg.gif|left|200px]]
 
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{{Structure
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==BETA-LACTAMASE FROM STREPTOMYCES ALBUS G==
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|PDB= 1bsg |SIZE=350|CAPTION= <scene name='initialview01'>1bsg</scene>, resolution 1.85&Aring;
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<StructureSection load='1bsg' size='340' side='right'caption='[[1bsg]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACT:ACETATE ION'>ACT</scene>
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<table><tr><td colspan='2'>[[1bsg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_albus_G Streptomyces albus G]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BSG FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bsg OCA], [https://pdbe.org/1bsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bsg RCSB], [https://www.ebi.ac.uk/pdbsum/1bsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bsg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLAC_STRAL BLAC_STRAL]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/1bsg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bsg ConSurf].
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<div style="clear:both"></div>
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'''BETA-LACTAMASE FROM STREPTOMYCES ALBUS G'''
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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==Overview==
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</StructureSection>
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The crystal structure of the beta-lactamase of Streptomyces albus G has been solved at 0.3 nm resolution by X-ray-diffraction methods. The enzyme is a typical two-domain protein. One domain consists of five alpha-helices, and the other is five-stranded beta-sheet with alpha-helices on both sides of the sheet. The active-site serine residue (Ser-48) is within a cleft located between the two domains.
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[[Category: Large Structures]]
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[[Category: Streptomyces albus G]]
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==About this Structure==
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[[Category: Charlier P]]
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1BSG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_albus_g Streptomyces albus g]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSG OCA].
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[[Category: Dideberg O]]
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[[Category: Fonze E]]
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==Reference==
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The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution., Dideberg O, Charlier P, Wery JP, Dehottay P, Dusart J, Erpicum T, Frere JM, Ghuysen JM, Biochem J. 1987 Aug 1;245(3):911-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/3499147 3499147]
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[[Category: Beta-lactamase]]
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[[Category: Single protein]]
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[[Category: Streptomyces albus g]]
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[[Category: Charlier, P.]]
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[[Category: Dideberg, O.]]
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[[Category: Fonze, E.]]
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[[Category: ACT]]
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[[Category: antibiotic resistance]]
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[[Category: hydrolase]]
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[[Category: penicillin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:15:10 2008''
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Current revision

BETA-LACTAMASE FROM STREPTOMYCES ALBUS G

PDB ID 1bsg

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