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1bxk

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[[Image:1bxk.jpg|left|200px]]
 
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{{Structure
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==DTDP-GLUCOSE 4,6-DEHYDRATASE FROM E. COLI==
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|PDB= 1bxk |SIZE=350|CAPTION= <scene name='initialview01'>1bxk</scene>, resolution 1.9&Aring;
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<StructureSection load='1bxk' size='340' side='right'caption='[[1bxk]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
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<table><tr><td colspan='2'>[[1bxk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BXK FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/dTDP-glucose_4,6-dehydratase dTDP-glucose 4,6-dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.46 4.2.1.46]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxk OCA], [https://pdbe.org/1bxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bxk RCSB], [https://www.ebi.ac.uk/pdbsum/1bxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxk ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RMLB2_ECOLI RMLB2_ECOLI] Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.<ref>PMID:7559340</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/1bxk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bxk ConSurf].
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<div style="clear:both"></div>
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'''DTDP-GLUCOSE 4,6-DEHYDRATASE FROM E. COLI'''
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==See Also==
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*[[DTDP-glucose 4%2C6-dehydratase|DTDP-glucose 4%2C6-dehydratase]]
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== References ==
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==About this Structure==
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<references/>
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1BXK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXK OCA].
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: dTDP-glucose 4,6-dehydratase]]
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[[Category: Frey PA]]
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[[Category: Frey, P A.]]
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[[Category: Hegeman AD]]
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[[Category: Hegeman, A D.]]
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[[Category: Holden HM]]
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[[Category: Holden, H M.]]
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[[Category: Thoden JB]]
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[[Category: Thoden, J B.]]
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[[Category: NAD]]
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[[Category: dehydratase]]
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[[Category: dehydrogenase]]
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[[Category: epimerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:17:05 2008''
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Current revision

DTDP-GLUCOSE 4,6-DEHYDRATASE FROM E. COLI

PDB ID 1bxk

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