This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1c1k
From Proteopedia
(Difference between revisions)
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:1c1k.png|left|200px]] | ||
| - | + | ==BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN== | |
| - | + | <StructureSection load='1c1k' size='340' side='right'caption='[[1c1k]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1c1k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C1K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IR:IRIDIUM+ION'>IR</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c1k OCA], [https://pdbe.org/1c1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c1k RCSB], [https://www.ebi.ac.uk/pdbsum/1c1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c1k ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/HLOAD_BPT4 HLOAD_BPT4] DNA helicase loader protein that participates in viral DNA replication, recombination, and repair (PubMed:10871615). At the fork, required for loading of the replicative helicase onto DNA protected by the ssDNA-binding protein (PubMed:11459967, PubMed:7806533, PubMed:10871615, PubMed:22427673). Coordinates simultaneous synthesis of leading- and lagging-strands (PubMed:11459969).[HAMAP-Rule:MF_04156]<ref>PMID:10871615</ref> <ref>PMID:11459967</ref> <ref>PMID:22427673</ref> <ref>PMID:7806533</ref> <ref>PMID:11459969</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c1/1c1k_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c1k ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | == | + | == References == |
| - | + | <references/> | |
| - | [ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [[ | + | [[Category: Escherichia virus T4]] |
| - | [ | + | [[Category: Large Structures]] |
| - | [[ | + | [[Category: Hyde CC]] |
| - | [[Category: | + | [[Category: Jones CE]] |
| - | [[Category: | + | [[Category: Mueser TC]] |
| - | [[Category: | + | [[Category: Nossal NG]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN
| |||||||||||

