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1c9j

From Proteopedia

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{{Seed}}
 
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[[Image:1c9j.png|left|200px]]
 
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==BACILLUS LENTUS SUBTILISIN K27R/N87S/V104Y/N123S/T274A VARIANT==
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The line below this paragraph, containing "STRUCTURE_1c9j", creates the "Structure Box" on the page.
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<StructureSection load='1c9j' size='340' side='right'caption='[[1c9j]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1c9j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lederbergia_lenta Lederbergia lenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C9J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1c9j| PDB=1c9j | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c9j OCA], [https://pdbe.org/1c9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c9j RCSB], [https://www.ebi.ac.uk/pdbsum/1c9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c9j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SUBS_LEDLE SUBS_LEDLE] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/1c9j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c9j ConSurf].
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<div style="clear:both"></div>
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===BACILLUS LENTUS SUBTILISIN K27R/N87S/V104Y/N123S/T274A VARIANT===
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==See Also==
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*[[Subtilisin 3D structures|Subtilisin 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10493860}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10493860 is the PubMed ID number.
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[[Category: Lederbergia lenta]]
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[[Category: Bott R]]
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{{ABSTRACT_PUBMED_10493860}}
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==About this Structure==
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1C9J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_lentus Bacillus lentus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9J OCA].
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==Reference==
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Engineered Bacillus lentus subtilisins having altered flexibility., Graycar T, Knapp M, Ganshaw G, Dauberman J, Bott R, J Mol Biol. 1999 Sep 10;292(1):97-109. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10493860 10493860]
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[[Category: Bacillus lentus]]
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[[Category: Single protein]]
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[[Category: Subtilisin]]
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[[Category: Bott, R.]]
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[[Category: Altered flexibility]]
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[[Category: Hydrolase]]
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[[Category: Subtilisin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:24:30 2008''
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Current revision

BACILLUS LENTUS SUBTILISIN K27R/N87S/V104Y/N123S/T274A VARIANT

PDB ID 1c9j

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