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1cxv

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[[Image:1cxv.png|left|200px]]
 
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{{STRUCTURE_1cxv| PDB=1cxv | SCENE= }}
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==STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)==
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<StructureSection load='1cxv' size='340' side='right'caption='[[1cxv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1cxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CXV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10525409}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CBP:2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE'>CBP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cxv OCA], [https://pdbe.org/1cxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cxv RCSB], [https://www.ebi.ac.uk/pdbsum/1cxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cxv ProSAT]</span></td></tr>
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[[1cxv]] is a 2 chain structure of [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MMP13_MOUSE MMP13_MOUSE] Degrades collagen type I.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/1cxv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cxv ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Matrix metalloproteinase|Matrix metalloproteinase]]
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*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010525409</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Botos, I.]]
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[[Category: Botos I]]
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[[Category: Eeckhout, Y.]]
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[[Category: Eeckhout Y]]
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[[Category: Lemaitre, V.]]
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[[Category: Lemaitre V]]
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[[Category: Meyer, E.]]
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[[Category: Meyer E]]
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[[Category: Meyer, E F.]]
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[[Category: Meyer EF]]
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[[Category: Swanson, S M.]]
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[[Category: Swanson SM]]
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[[Category: Collagen degradation]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Metalloprotease]]
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Current revision

STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)

PDB ID 1cxv

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