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1dc0

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[[Image:1dc0.gif|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG==
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|PDB= 1dc0 |SIZE=350|CAPTION= <scene name='initialview01'>1dc0</scene>, resolution 1.3&Aring;
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<StructureSection load='1dc0' size='340' side='right'caption='[[1dc0]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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<table><tr><td colspan='2'>[[1dc0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DC0 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dc0 OCA], [https://pdbe.org/1dc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dc0 RCSB], [https://www.ebi.ac.uk/pdbsum/1dc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dc0 ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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__TOC__
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dc0 OCA], [http://www.ebi.ac.uk/pdbsum/1dc0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dc0 RCSB]</span>
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</StructureSection>
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}}
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[[Category: Large Structures]]
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[[Category: Dickerson RE]]
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'''CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG'''
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[[Category: Kopka ML]]
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[[Category: Ng HL]]
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==Overview==
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The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A &lt;--&gt; B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition.
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==About this Structure==
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1DC0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC0 OCA].
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==Reference==
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The structure of a stable intermediate in the A &lt;--&gt; B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10688897 10688897]
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[[Category: Protein complex]]
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[[Category: Dickerson, R E.]]
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[[Category: Kopka, M L.]]
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[[Category: Ng, H. L.]]
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[[Category: a-dna]]
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[[Category: b-dna]]
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[[Category: intermediate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:38:35 2008''
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Current revision

CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG

PDB ID 1dc0

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