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1dnm

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(New page: 200px<br /><applet load="1dnm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dnm, resolution 2.500&Aring;" /> '''CRYSTAL STRUCTURE A...)
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[[Image:1dnm.gif|left|200px]]<br /><applet load="1dnm" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1dnm, resolution 2.500&Aring;" />
 
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'''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''<br />
 
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==Overview==
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==CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)==
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The crystal structure of the dodecanucleotide d(CGCAAGCTGGCG) has been, determined to a resolution of 2.5 A and refined to an R factor of 19.3%, for 1710 reflections. The sequence crystallizes as a B-type double helix, with two G(anti).A(syn) base pairs. These are stabilized by three-center, hydrogen bonds to pyrimidines that induce perturbations in base-pair, geometry. The central AGCT region of the helix has a wide (greater than 6, A) minor groove.
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<StructureSection load='1dnm' size='340' side='right'caption='[[1dnm]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1dnm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNM FirstGlance]. <br>
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1DNM is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnm OCA], [https://pdbe.org/1dnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnm RCSB], [https://www.ebi.ac.uk/pdbsum/1dnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnm ProSAT]</span></td></tr>
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==Reference==
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</table>
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Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2395870 2395870]
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__TOC__
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[[Category: Protein complex]]
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</StructureSection>
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[[Category: Li, B.F.]]
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[[Category: Large Structures]]
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[[Category: Neidle, S.]]
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[[Category: Li BF]]
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[[Category: Sanderson, M.R.]]
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[[Category: Neidle S]]
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[[Category: Skelly, J.V.]]
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[[Category: Sanderson MR]]
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[[Category: Swann, P.F.]]
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[[Category: Skelly JV]]
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[[Category: Tickle, I.J.]]
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[[Category: Swann PF]]
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[[Category: Webster, G.D.]]
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[[Category: Tickle IJ]]
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[[Category: b-dna]]
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[[Category: Webster GD]]
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[[Category: double helix]]
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[[Category: mismatched]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 03:23:55 2007''
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Current revision

CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)

PDB ID 1dnm

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