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1dpl
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==A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE== | ==A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE== | ||
| - | <StructureSection load='1dpl' size='340' side='right' caption='[[1dpl]], [[Resolution|resolution]] 0.83Å' scene=''> | + | <StructureSection load='1dpl' size='340' side='right'caption='[[1dpl]], [[Resolution|resolution]] 0.83Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1dpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[1dpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPL FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.83Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=T23:2-O-METHYL-3-METHYL-3-DEOXY-ARABINOFURANOSYL-THYMINE-5-PHOSPHATE'>T23</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpl OCA], [https://pdbe.org/1dpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpl RCSB], [https://www.ebi.ac.uk/pdbsum/1dpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpl ProSAT]</span></td></tr> |
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition. | ||
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| - | X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.,Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M Biopolymers. 1998;48(4):234-52. PMID:10699842<ref>PMID:10699842</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: An | + | [[Category: Large Structures]] |
| - | [[Category: Cook | + | [[Category: An H]] |
| - | [[Category: Egli | + | [[Category: Dan Cook P]] |
| - | [[Category: Joachimiak | + | [[Category: Egli M]] |
| - | [[Category: Maier | + | [[Category: Joachimiak A]] |
| - | [[Category: Manoharan | + | [[Category: Maier MA]] |
| - | [[Category: Miller | + | [[Category: Manoharan M]] |
| - | [[Category: Minasov | + | [[Category: Miller R]] |
| - | [[Category: Sanishvili | + | [[Category: Minasov G]] |
| - | [[Category: Teplova | + | [[Category: Sanishvili R]] |
| - | [[Category: Tereshko | + | [[Category: Teplova M]] |
| - | [[Category: Weeks | + | [[Category: Tereshko V]] |
| - | + | [[Category: Weeks CM]] | |
| - | + | ||
| - | + | ||
Current revision
A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE
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Categories: Large Structures | An H | Dan Cook P | Egli M | Joachimiak A | Maier MA | Manoharan M | Miller R | Minasov G | Sanishvili R | Teplova M | Tereshko V | Weeks CM
