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1dtj

From Proteopedia

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[[Image:1dtj.png|left|200px]]
 
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{{STRUCTURE_1dtj| PDB=1dtj | SCENE= }}
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==CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN==
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<StructureSection load='1dtj' size='340' side='right'caption='[[1dtj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dtj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10368286}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dtj OCA], [https://pdbe.org/1dtj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dtj RCSB], [https://www.ebi.ac.uk/pdbsum/1dtj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dtj ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1dtj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTJ OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/NOVA2_HUMAN NOVA2_HUMAN] May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:010368286</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/1dtj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dtj ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Buckanovich, R J.]]
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[[Category: Large Structures]]
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[[Category: Burley, S K.]]
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[[Category: Buckanovich RJ]]
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[[Category: Chen, H.]]
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[[Category: Burley SK]]
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[[Category: Darnell, R B.]]
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[[Category: Chen H]]
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[[Category: Edo, C.]]
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[[Category: Darnell RB]]
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[[Category: Lewis, H A.]]
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[[Category: Edo C]]
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[[Category: Musunuru, K.]]
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[[Category: Lewis HA]]
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[[Category: Yang, Y Y.L.]]
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[[Category: Musunuru K]]
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[[Category: Zhong, R.]]
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[[Category: Yang YYL]]
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[[Category: Alpha-beta fold rna-binding motif]]
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[[Category: Zhong R]]
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[[Category: Immune system]]
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[[Category: Kh domain]]
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Current revision

CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN

PDB ID 1dtj

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