1enh

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{{Seed}}
 
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[[Image:1enh.png|left|200px]]
 
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==STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN==
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The line below this paragraph, containing "STRUCTURE_1enh", creates the "Structure Box" on the page.
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<StructureSection load='1enh' size='340' side='right'caption='[[1enh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1enh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ENH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ENH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1enh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1enh OCA], [https://pdbe.org/1enh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1enh RCSB], [https://www.ebi.ac.uk/pdbsum/1enh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1enh ProSAT]</span></td></tr>
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{{STRUCTURE_1enh| PDB=1enh | SCENE= }}
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</table>
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== Function ==
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===STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN===
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[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_7849596}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 7849596 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1enh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_7849596}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1enh ConSurf].
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1ENH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ENH OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structural studies of the engrailed homeodomain., Clarke ND, Kissinger CR, Desjarlais J, Gilliland GL, Pabo CO, Protein Sci. 1994 Oct;3(10):1779-87. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7849596 7849596]
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Clarke, N D.]]
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[[Category: Clarke ND]]
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[[Category: Desjarlais, J.]]
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[[Category: Desjarlais J]]
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[[Category: Gilliland, G L.]]
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[[Category: Gilliland GL]]
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[[Category: Kissinger, C R.]]
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[[Category: Kissinger CR]]
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[[Category: Pabo, C O.]]
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[[Category: Pabo CO]]
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[[Category: Dna-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:04:41 2008''
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Current revision

STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN

PDB ID 1enh

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