1es6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:06, 7 February 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1es6.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF THE MATRIX PROTEIN OF EBOLA VIRUS==
-
The line below this paragraph, containing "STRUCTURE_1es6", creates the "Structure Box" on the page.
+
<StructureSection load='1es6' size='340' side='right'caption='[[1es6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1es6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ebola_virus_sp. Ebola virus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ES6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ES6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1es6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1es6 OCA], [https://pdbe.org/1es6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1es6 RCSB], [https://www.ebi.ac.uk/pdbsum/1es6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1es6 ProSAT]</span></td></tr>
-
{{STRUCTURE_1es6| PDB=1es6 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===CRYSTAL STRUCTURE OF THE MATRIX PROTEIN OF EBOLA VIRUS===
+
[https://www.uniprot.org/uniprot/VP40_EBOZ5 VP40_EBOZ5] Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).[UniProtKB:Q05128]
-
 
+
__TOC__
-
 
+
</StructureSection>
-
<!--
+
[[Category: Ebola virus sp]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_10944105}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 10944105 is the PubMed ID number.
+
[[Category: Dessen A]]
-
-->
+
[[Category: Dolnik O]]
-
{{ABSTRACT_PUBMED_10944105}}
+
[[Category: Klenk H-D]]
-
 
+
[[Category: Volchkov V]]
-
==About this Structure==
+
[[Category: Weissenhorn W]]
-
1ES6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ebola_virus_sp. Ebola virus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ES6 OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of the matrix protein VP40 from Ebola virus., Dessen A, Volchkov V, Dolnik O, Klenk HD, Weissenhorn W, EMBO J. 2000 Aug 15;19(16):4228-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10944105 10944105]
+
-
[[Category: Ebola virus sp.]]
+
-
[[Category: Single protein]]
+
-
[[Category: Dessen, A.]]
+
-
[[Category: Dolnik, O.]]
+
-
[[Category: Klenk, H D.]]
+
-
[[Category: Volchkov, V.]]
+
-
[[Category: Weissenhorn, W.]]
+
-
[[Category: Anti-parallel strand]]
+
-
[[Category: Beta sandwich]]
+
-
[[Category: Beta sheet]]
+
-
[[Category: Helix]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:47:40 2008''
+

Current revision

CRYSTAL STRUCTURE OF THE MATRIX PROTEIN OF EBOLA VIRUS

PDB ID 1es6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1es6"
Personal tools