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1exm

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==CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP.==
==CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP.==
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<StructureSection load='1exm' size='340' side='right' caption='[[1exm]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1exm' size='340' side='right'caption='[[1exm]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1exm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EXM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1exm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EXM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1exm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1exm OCA], [http://pdbe.org/1exm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1exm RCSB], [http://www.ebi.ac.uk/pdbsum/1exm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1exm ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1exm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1exm OCA], [https://pdbe.org/1exm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1exm RCSB], [https://www.ebi.ac.uk/pdbsum/1exm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1exm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EFTU1_THETH EFTU1_THETH]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
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[https://www.uniprot.org/uniprot/EFTU1_THETH EFTU1_THETH] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Elongation factor|Elongation factor]]
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Hilgenfeld, R]]
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[[Category: Hilgenfeld R]]
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[[Category: Hogg, T]]
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[[Category: Hogg T]]
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[[Category: Mesters, J R]]
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[[Category: Mesters JR]]
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[[Category: Chaperone]]
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[[Category: Disulfide isomerase]]
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[[Category: Gtpase]]
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[[Category: Molecular switch]]
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[[Category: Q-beta replicase]]
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[[Category: Ribosome]]
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[[Category: Translation]]
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[[Category: Trna]]
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Current revision

CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP.

PDB ID 1exm

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