1f1z

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[[Image:1f1z.png|left|200px]]
 
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{{STRUCTURE_1f1z| PDB=1f1z | SCENE= }}
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==TNSA, a catalytic component of the TN7 transposition system==
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<StructureSection load='1f1z' size='340' side='right'caption='[[1f1z]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1f1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F1Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f1z OCA], [https://pdbe.org/1f1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f1z RCSB], [https://www.ebi.ac.uk/pdbsum/1f1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f1z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TNSA_ECOLX TNSA_ECOLX] Required for Tn7 transposition. Forms the transposase, together with TnsB. TnsA executes the 5'-DNA strand breakage reaction. TnsABC and TnsD promote high-frequency insertion of Tn7 into a specific target site known as ATT-Tn7 whereas TnsABC and TnsD promote low-frequency insertion into many different sites.<ref>PMID:8947057</ref> <ref>PMID:10704304</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/1f1z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f1z ConSurf].
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<div style="clear:both"></div>
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===TNSA, a catalytic component of the TN7 transposition system===
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==See Also==
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*[[Transposase 3D structures|Transposase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[1f1z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1Z OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:010911996</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Craig, N L.]]
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[[Category: Large Structures]]
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[[Category: Dyda, F.]]
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[[Category: Craig NL]]
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[[Category: Hickman, A B.]]
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[[Category: Dyda F]]
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[[Category: Li, Y.]]
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[[Category: Hickman AB]]
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[[Category: Mathew, S V.]]
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[[Category: Li Y]]
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[[Category: May, E W.]]
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[[Category: Mathew SV]]
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[[Category: Dna binding protein]]
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[[Category: May EW]]
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[[Category: Restriction endonuclease fold]]
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Current revision

TNSA, a catalytic component of the TN7 transposition system

PDB ID 1f1z

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