1fca

<table><tr><td colspan='2'>[[1fca]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_acidi-urici"_liebert_1909 "bacillus acidi-urici" liebert 1909]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FCA FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fca OCA], [http://pdbe.org/1fca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fca RCSB], [http://www.ebi.ac.uk/pdbsum/1fca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fca ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/FER_CLOAC FER_CLOAC]] Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

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== Publication Abstract from PubMed ==

Ferredoxins (Fd) are electron-carrier proteins, the active sites of which are organized around clusters made of iron and inorganic sulfur. The Fd from Clostridium acidurici is 55 amino acids long and contains two [4Fe-4S] clusters. Crystals have been obtained in the space group P4(3)2(1)2, a = b = 34.441 (5), c = 74.778 (9) A. The structure was solved by molecular replacement using the Fd from Peptostreptcoccus asaccharolyticus as a search model, these two ferredoxins having 37 residues in common. Refinement using molecular-dynamics techniques was then initiated. Successive rounds of model building and refinement gave a structure that includes 45 water molecules with R = 15%. At this stage, the electron-density map clearly revealed discrepancies in the position of two amino acids in the published primary sequence. Refinement based on these modifications led to R = 14.3% for 3921 reflections up to 1.8 A, resolution. The geometry of the two clusters has been found to be in good agreement with that previously obtained at a lower resolution. Interactions of polypeptide chain with the [4Fe-4S] clusters, the cluster geometry as well as the hydrogen bonds involving S, Sgamma, N and water molecules are reported.

Structure of the ferredoxin from Clostridium acidurici: model at 1.8 A resolution.,TranQui D, Jesior JC Acta Crystallogr D Biol Crystallogr. 1995 Mar 1;51(Pt 2):155-9. PMID:15299316<ref>PMID:15299316</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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== References ==

<references/>

[[Category: Bacillus acidi-urici liebert 1909]]

[[Category: Jesior, J C]]

[[Category: Tranqui, D]]