1fmt
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1fmt.png|left|200px]] | ||
- | + | ==METHIONYL-TRNAFMET FORMYLTRANSFERASE FROM ESCHERICHIA COLI== | |
- | + | <StructureSection load='1fmt' size='340' side='right'caption='[[1fmt]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1fmt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FMT FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fmt OCA], [https://pdbe.org/1fmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fmt RCSB], [https://www.ebi.ac.uk/pdbsum/1fmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fmt ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/FMT_ECOLI FMT_ECOLI] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP. | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | < | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/1fmt_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fmt ConSurf]. |
- | + | <div style="clear:both"></div> | |
- | + | __TOC__ | |
- | == | + | </StructureSection> |
- | < | + | |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Mechulam | + | [[Category: Mechulam Y]] |
- | [[Category: Schmitt | + | [[Category: Schmitt E]] |
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Current revision
METHIONYL-TRNAFMET FORMYLTRANSFERASE FROM ESCHERICHIA COLI
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